Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?
Eddy and Sin discuss the study by Patel and colleagues on pulmonary vasculature on CT imaging and its physiologic and hematologic correlates in mechanically ventilated patients with severe COVID-19 pneumonia. This retrospective study included 39 consecutive patients with acute COVID-19 respiratory f...
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Veröffentlicht in: | American journal of respiratory and critical care medicine 2020-09, Vol.202 (5), p.642-644 |
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description | Eddy and Sin discuss the study by Patel and colleagues on pulmonary vasculature on CT imaging and its physiologic and hematologic correlates in mechanically ventilated patients with severe COVID-19 pneumonia. This retrospective study included 39 consecutive patients with acute COVID-19 respiratory failure who showed increased physiologic dead space as evidenced by reduced dynamic compliance (mean, 33.7 ml/cm H2O) and elevated ventilatory ratio (mean, 2.6), in agreement with previous results and suggestive of marked vascular involvement. Pulmonary vascular abnormalities were assessed by the presence of dilated peripheral vessels, identified as a vascular "tree-in-bud" pattern, as well as pulmonary perfusion abnormalities in a subset of 18 patients who were able to undergo dual-energy CT imaging. |
doi_str_mv | 10.1164/rccm.202007-2833ED |
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Pulmonary vascular abnormalities were assessed by the presence of dilated peripheral vessels, identified as a vascular "tree-in-bud" pattern, as well as pulmonary perfusion abnormalities in a subset of 18 patients who were able to undergo dual-energy CT imaging.</description><identifier>ISSN: 1073-449X</identifier><identifier>EISSN: 1535-4970</identifier><identifier>DOI: 10.1164/rccm.202007-2833ED</identifier><identifier>PMID: 32687386</identifier><language>eng</language><publisher>United States: American Thoracic Society</publisher><subject>Betacoronavirus ; Biomarkers ; Coronavirus Infections ; COVID-19 ; Humans ; Lung ; Medical imaging ; Medical prognosis ; Pandemics ; Pneumonia ; Pneumonia, Viral ; Prognosis ; Respiratory failure ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; Tomography</subject><ispartof>American journal of respiratory and critical care medicine, 2020-09, Vol.202 (5), p.642-644</ispartof><rights>Copyright American Thoracic Society Sep 1, 2020</rights><rights>Copyright © 2020 by the American Thoracic Society 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-aaa109a275d87cb8030db16236e083676b782f19b85f1984b7bbe3890b91cbef3</citedby><cites>FETCH-LOGICAL-c430t-aaa109a275d87cb8030db16236e083676b782f19b85f1984b7bbe3890b91cbef3</cites><orcidid>0000-0002-0756-6643 ; 0000-0002-2541-1645</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,4023,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32687386$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eddy, Rachel L</creatorcontrib><creatorcontrib>Sin, Don D</creatorcontrib><title>Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?</title><title>American journal of respiratory and critical care medicine</title><addtitle>Am J Respir Crit Care Med</addtitle><description>Eddy and Sin discuss the study by Patel and colleagues on pulmonary vasculature on CT imaging and its physiologic and hematologic correlates in mechanically ventilated patients with severe COVID-19 pneumonia. 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Pulmonary vascular abnormalities were assessed by the presence of dilated peripheral vessels, identified as a vascular "tree-in-bud" pattern, as well as pulmonary perfusion abnormalities in a subset of 18 patients who were able to undergo dual-energy CT imaging.</description><subject>Betacoronavirus</subject><subject>Biomarkers</subject><subject>Coronavirus Infections</subject><subject>COVID-19</subject><subject>Humans</subject><subject>Lung</subject><subject>Medical imaging</subject><subject>Medical prognosis</subject><subject>Pandemics</subject><subject>Pneumonia</subject><subject>Pneumonia, Viral</subject><subject>Prognosis</subject><subject>Respiratory failure</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Tomography</subject><issn>1073-449X</issn><issn>1535-4970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1LHTEUhoNU_Kp_oIsS6KabaL5mknTRotevC1K7uEqhi5BkcsfYmck1mRH890auFe0mCeQ57zmHB4BPBB8QUvPD5Fx_QDHFWCAqGTs92QA7pGIV4krgD-WNBUOcq9_bYDfnO4wJlQRvgW1GaymYrHfAn1nsV9PoG7iIfWyTWd0-whuT3dSZBBfJexQGdDw13-AR_BkffAd_pdgOMY_BwXlv2jC08DjE3qS_PsEwwNnVzfwEEfXjI9hcmi77_Zd7D1yfnS5mF-jy6nw-O7pEjjM8ImMMwcpQUTVSOCsxw40lNWW1x5LVorZC0iVRVlbllNwKaz2TCltFnPVLtge-r3NXk-194_wwJtPpVQplqEcdTdDvf4Zwq9v4oAUvXRQvAV9fAlK8n3wedR-y811nBh-nrCmnlVQV4aKgX_5D7-KUhrJeoThVdUUqWSi6plyKOSe_fB2GYP3sTj-702t3eu2uFH1-u8ZryT9Z7AnY4ZTv</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Eddy, Rachel L</creator><creator>Sin, Don D</creator><general>American Thoracic Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-0756-6643</orcidid><orcidid>https://orcid.org/0000-0002-2541-1645</orcidid></search><sort><creationdate>20200901</creationdate><title>Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?</title><author>Eddy, Rachel L ; Sin, Don D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-aaa109a275d87cb8030db16236e083676b782f19b85f1984b7bbe3890b91cbef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Betacoronavirus</topic><topic>Biomarkers</topic><topic>Coronavirus Infections</topic><topic>COVID-19</topic><topic>Humans</topic><topic>Lung</topic><topic>Medical imaging</topic><topic>Medical prognosis</topic><topic>Pandemics</topic><topic>Pneumonia</topic><topic>Pneumonia, Viral</topic><topic>Prognosis</topic><topic>Respiratory failure</topic><topic>SARS-CoV-2</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eddy, Rachel L</creatorcontrib><creatorcontrib>Sin, Don D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of respiratory and critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eddy, Rachel L</au><au>Sin, Don D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?</atitle><jtitle>American journal of respiratory and critical care medicine</jtitle><addtitle>Am J Respir Crit Care Med</addtitle><date>2020-09-01</date><risdate>2020</risdate><volume>202</volume><issue>5</issue><spage>642</spage><epage>644</epage><pages>642-644</pages><issn>1073-449X</issn><eissn>1535-4970</eissn><abstract>Eddy and Sin discuss the study by Patel and colleagues on pulmonary vasculature on CT imaging and its physiologic and hematologic correlates in mechanically ventilated patients with severe COVID-19 pneumonia. 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source | MEDLINE; American Thoracic Society (ATS) Journals Online; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Betacoronavirus Biomarkers Coronavirus Infections COVID-19 Humans Lung Medical imaging Medical prognosis Pandemics Pneumonia Pneumonia, Viral Prognosis Respiratory failure SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Tomography |
title | Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19? |
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