Dietary supplementation with long-chain monounsaturated fatty acid isomers decreases atherosclerosis and alters lipoprotein proteomes in LDLr−/− mice

Abstract Background and aims Concentrated fish oils, containing a mixture of long-chain monounsaturated fatty acids (LCMUFA) with aliphatic chains longer than 18 C atoms (i.e., C20:1 and C22:1), have been shown to attenuate atherosclerosis development in mouse models. It is not clear, however, how i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Atherosclerosis 2017-07, Vol.262, p.31-38
Hauptverfasser:	Yang, Zhi-Hong, Gordon, Scott M, Sviridov, Denis, Wang, Shuibang, Danner, Robert L, Pryor, Milton, Vaisman, Boris, Shichijo, Yuka, Doisaki, Nobushige, Remaley, Alan T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aortic Diseases - blood Aortic Diseases - genetics Aortic Diseases - prevention & control Atherosclerosis Atherosclerosis - blood Atherosclerosis - genetics Atherosclerosis - pathology Atherosclerosis - prevention & control Biomarkers - blood C-Reactive Protein - metabolism Cardiovascular Cholesterol efflux Chromatography, Liquid Diet, Western Dietary Supplements Disease Models, Animal Fatty Acids, Monounsaturated - pharmacology Fish Oils - pharmacology Genetic Predisposition to Disease Hep G2 Cells Humans Hyperlipidemias - blood Hyperlipidemias - drug therapy Hyperlipidemias - genetics Hyperlipidemias - pathology Inflammation Lipoprotein proteome Lipoproteins - blood Liver - drug effects Liver - metabolism Long-chain monounsaturated fatty acids Mice, Knockout Peroxisome proliferator-activated receptors Peroxisome Proliferator-Activated Receptors - genetics Peroxisome Proliferator-Activated Receptors - metabolism Phenotype Plaque, Atherosclerotic Proteome Proteomics - methods Receptors, LDL - deficiency Receptors, LDL - genetics Tandem Mass Spectrometry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!