Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus

Smallpox, a contagious and deadly disease caused by variola virus, was eradicated by a strategy that included vaccination with vaccinia virus, a live-virus vaccine. Because the threat of bioterrorism with smallpox persists and infections with zoonotic poxvirus infections like monkeypox continue, and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2020-08, Vol.38 (38), p.6007-6018
Hauptverfasser:	Xiao, Yuhong, Zeng, Yuhong, Schante, Carole, Joshi, Sangeeta B., Buchman, George W., Volkin, David B., Middaugh, C. Russell, Isaacs, Stuart N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, aluminum hydroxide Adsorption Aluminum Aluminum Hydroxide Amino acids Animals Antibodies Antibodies, Viral Antibody responses Antigens Bioterrorism Cell culture CpG islands CpG oligonucleotide Gene banks Immune response Immunoglobulin G Mice Mice, Inbred BALB C Monkeypox, vaccinia virus Mpox Oligonucleotides Pharmaceutical industry Proteins Short term Smallpox Smallpox - prevention & control Smallpox Vaccine Smallpox, variola virus Survival Vaccination Vaccines Vaccines, Subunit Vaccinia virus Variola virus Viruses Weight loss Zoonoses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!