Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Chlamydia trachomatis Virulence-Associated Protease CPAF

CPAF (chlamydial protease-like activity factor) is a Chlamydia trachomatis protease that is translocated into the host cytosol during infection. CPAF activity results in dampened host inflammation signaling, cytoskeletal remodeling, and suppressed neutrophil activation. Although CPAF is an emerging...

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Veröffentlicht in:Biochemistry (Easton) 2019-08, Vol.58 (33), p.3527-3536
Hauptverfasser: Dudiak, Brianne M, Maksimchuk, Kenneth R, Bednar, Maria M, Podracky, Christopher J, Burg, Jonathan M, Nguyen, Tri M, Nwogbo, Felix O, Valdivia, Raphael H, McCafferty, Dewey G
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Sprache:eng
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