Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy

Activation of the innate immune system and natural killer (NK) cells has been a key effort in cancer immunotherapy research. Here, we report a nanoparticle-based trispecific NK cell engager (nano-TriNKE) platform that can target epidermal growth factor receptor (EGFR)-overexpressing tumors and promo...

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Veröffentlicht in:	Science advances 2020-07, Vol.6 (27), p.eaba8564
Hauptverfasser:	Au, Kin Man, Park, Steven I, Wang, Andrew Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied Sciences and Engineering Cancer ErbB Receptors Humans Immunotherapy Killer Cells, Natural Lymphocyte Activation Neoplasms - drug therapy SciAdv r-articles
Online-Zugang:	Volltext
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