Effect of a DPP-4 Inhibitor on Orthodontic Tooth Movement and Associated Root Resorption

Objectives. Dipeptidyl peptidase-4 (DPP-4) inhibitors are used as a treatment for type 2 diabetes mellitus and have also recently been applied to enhance bone quality and density, and increase the expression of bone markers. This study aimed to investigate the effect of a DPP-4 inhibitor on orthodon...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-9
Hauptverfasser:	Mizoguchi, Itaru, Adya, Pramusita, Marahleh, Aseel, Noguchi, Takahiro, Ohori, Fumitoshi, Ogawa, Saika, Shen, Wei-Ren, Kitaura, Hideki, Qi, Jiawei, Nara, Yasuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical materials Bone density Cytokines Diabetes mellitus Diabetes mellitus (non-insulin dependent) Dipeptidyl-peptidase IV Dipeptidyl-Peptidase IV Inhibitors - pharmacology Fractures Gene expression Inhibitors Male Maxilla Mechanical loading Metabolism Mice Mice, Inbred C57BL Microscopy Models, Animal Molar - drug effects Molar - metabolism Nickel Nickel - pharmacology Odontoclasts Orthodontics Osteoclastogenesis Osteoclasts Osteoclasts - drug effects Osteoclasts - metabolism Osteogenesis - drug effects Peptidase Physiological aspects RANK Ligand - metabolism Root resorption Root Resorption - drug therapy Root Resorption - metabolism Silicones Teeth Titanium Titanium - pharmacology Tooth Movement Techniques - methods Tooth Root - drug effects Tooth Root - metabolism TRANCE protein Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!