Development of Tissue Engineered Heart Valves for Percutaneous Transcatheter Delivery in a Fetal Ovine Model

[Display omitted] •A fully biodegradable fetal valve was developed using a zinc-aluminum alloy stent and electrospun PCL leaflets.•In vitro evaluation of the valve was performed with accelerated degradation, mechanical, and flow loop testing, and the valve showed trivial stenosis and trivial regurgi...

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Veröffentlicht in:	JACC. Basic to translational science 2020-08, Vol.5 (8), p.815-828
Hauptverfasser:	Zakko, Jason, Blum, Kevin M., Drews, Joseph D., Wu, Yen-Lin, Hatoum, Hoda, Russell, Madeleine, Gooden, Shelley, Heitkemper, Megan, Conroy, Olivia, Kelly, John, Carey, Stacey, Sacks, Michael, Texter, Karen, Ragsdale, Ellie, Strainic, James, Bocks, Martin, Wang, Yadong, Dasi, Lakshmi Prasad, Armstrong, Aimee K., Breuer, Christopher
Format:	Artikel
Sprache:	eng
Schlagworte:	congenital heart disease PRECLINICAL RESEARCH tissue-engineered heart valve transcatheter heart valve translational medicine
Online-Zugang:	Volltext
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