Randomised clinical trial: the benefit of combination therapy with adefovir and lamivudine for chronic hepatitis B

Summary Background Combination antiviral therapy holds the promise of increasing response rates while decreasing antiviral resistance, but has yet to be shown to be beneficial or necessary in chronic hepatitis B. Aim To evaluate the benefit of combination therapy with adefovir and lamivudine versus...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2012-05, Vol.35 (9), p.1027-1035
Hauptverfasser:	Ghany, M. G., Feld, J. J., Zhao, X., Heller, T., Doo, E., Rotman, Y., Nagabhyru, P., Koh, C., Kleiner, D. E., Wright, E. C., Liang, T. J., Hoofnagle, J. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - analogs & derivatives Adenine - therapeutic use Adult Antiviral Agents - administration & dosage Antiviral Agents - therapeutic use Biological and medical sciences Digestive system Drug Resistance, Viral Drug Therapy, Combination Female Gastroenterology. Liver. Pancreas. Abdomen Hepatitis B e Antigens - analysis Hepatitis B Surface Antigens - analysis Hepatitis B, Chronic - drug therapy Human viral diseases Humans Infectious diseases Lamivudine - administration & dosage Lamivudine - therapeutic use Male Medical sciences Middle Aged Organophosphonates - administration & dosage Organophosphonates - therapeutic use Pharmacology. Drug treatments Treatment Outcome Viral diseases Viral hepatitis
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