Pharmacogenomics of methadone: a narrative review of the literature

Methadone, a synthetic opioid with longer duration of action and lower abuse potential compared with morphine, is used to prevent opioid withdrawal, as well as to manage chronic and acute surgical pain. The variability in response to methadone has been widely recognized. The purpose of this article...

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Veröffentlicht in:	Pharmacogenomics 2020-08, Vol.21 (12), p.871-887
Hauptverfasser:	Packiasabapathy, Senthil, Aruldhas, Blessed W, Horn, Nicole, Overholser, Brian R, Quinney, Sara K, Renschler, Janelle S, Sadhasivam, Senthilkumar
Format:	Artikel
Sprache:	eng
Schlagworte:	gene variants methadone opioid opioid maintenance therapy personalized analgesia pharmacodynamics pharmacogenetics pharmacogenomics pharmacokinetics polymorphism Review
Online-Zugang:	Volltext
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