Transcriptomics Study to Determine the Molecular Mechanism by which sIL-13Rα2-Fc Inhibits Caudal Intervertebral Disc Degeneration in Rats

Background. Intervertebral disc degeneration is related to tissue fibrosis. ADAMTS can degrade the important components of the ECM during the process of intervertebral disc degeneration, ultimately resulting in the loss of intervertebral disc function. sIL-13Rα2-Fc can inhibit fibrosis and slow down...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2020-01, Vol.2020 (2020), p.1-13
Hauptverfasser:	Liu, Yang, Yuan, Wen, Chen, Jinlei, Fang, Pengzhong, Sun, Junhao, Tan, Jianshi, Wang, Xin, Chen, Huajiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Annotations Annuli Apoptosis Collagen Collagen (type I) Collagen (type II) Cytokines Degeneration Degenerative disc disease Degradation Extracellular matrix Fibroblast growth factor 1 Fibrosis Fluorescence Gene expression Genes Intervertebral discs Proteins Pulmonary fibrosis Real time Rodents Staining Superoxide dismutase Tissue inhibitor of metalloproteinase 1 Tissues Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!