Circular RNA circ_0026359 Enhances Cisplatin Resistance in Gastric Cancer via Targeting miR-1200/POLD4 Pathway

Human gastric cancer is one of the most common malignant tumors with a poor prognosis. Cisplatin (CDDP) is a well-known first-line chemotherapeutic drug. Acquired resistance retards the clinical application of CDDP in gastric cancer. In this study, circular RNA circ_0026359 was demonstrated to be ov...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-12
Hauptverfasser:	Zhang, Jiajia, Zhou, Bo, Yu, Xin, Zhang, Zongyao, Chang, Jiacong
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Cancer Cell growth Cell Line, Tumor Chemotherapy Circular RNA Cisplatin Cisplatin - pharmacology DNA Polymerase III - genetics DNA Polymerase III - metabolism Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - genetics Gastric cancer Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans Kaplan-Meier Estimate Medical research Methods MicroRNAs - genetics Plasmids Ribonucleic acid RNA RNA sequencing RNA, Circular - genetics Statistical analysis Stomach cancer Stomach Neoplasms - drug therapy Stomach Neoplasms - genetics Stomach Neoplasms - mortality Stomach Neoplasms - pathology Survival Survival Rate Tissues Tumors
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