CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly

CENP-B binds to CENP-B boxes on centromeric satellite DNAs (known as alphoid DNA in humans). CENP-B maintains kinetochore function through interactions with CENP-A nucleosomes and CENP-C. CENP-B binding to transfected alphoid DNA can induce CENP-A assembly, functional centromere and kinetochore form...

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Veröffentlicht in:	Journal of cell science 2020-08, Vol.133 (15)
Hauptverfasser:	Otake, Koichiro, Ohzeki, Jun-Ichirou, Shono, Nobuaki, Kugou, Kazuto, Okazaki, Koei, Nagase, Takahiro, Yamakawa, Hisashi, Kouprina, Natalay, Larionov, Vladimir, Kimura, Hiroshi, Earnshaw, William C, Masumoto, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantigens - genetics Centromere Centromere Protein A - genetics Chromatin - genetics Chromobox Protein Homolog 5 Chromosomal Proteins, Non-Histone - genetics Epigenesis, Genetic Heterochromatin - genetics Humans
Online-Zugang:	Volltext
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