Targeting the renin-angiotensin-aldosterone system in fibrosis

•The classical renin-angiotensin-aldosterone system (RAAS) has been implicated as an inducer of fibrosis in multiple tissue and organ types.•Recent evidence demonstrates that the alternative RAAS counteracts the classical RAAS to attenuate fibrosis.•Augmentation of the alternative RAAS, or altering...

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