Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis

The patient was a 70-year-old man with idiopathic orbital inflammation (IOI) that appeared on the severely affected side of preceding myasthenia gravis (MG). The patient was diagnosed with MG 5 years prior to the onset of IOI. When IOI was diagnosed, an edrophonium test was negative. IOI was conside...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Internal Medicine 2020/07/15, Vol.59(14), pp.1763-1767
Hauptverfasser: Fujita, Satoru, Furuta, Natsumi, Maruyama, Tokuzo, Tsukagoshi, Setsuki, Nagashima, Kazuaki, Fujita, Yukio, Nagai, Kazuki, Kashima, Tomoyuki, Tanaka, Makoto, Miki, Izumi, Yamazaki, Ayako, Ikota, Hayato, Oyama, Tetsunari, Ikeda, Yoshio
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1767
container_issue 14
container_start_page 1763
container_title Internal Medicine
container_volume 59
creator Fujita, Satoru
Furuta, Natsumi
Maruyama, Tokuzo
Tsukagoshi, Setsuki
Nagashima, Kazuaki
Fujita, Yukio
Nagai, Kazuki
Kashima, Tomoyuki
Tanaka, Makoto
Miki, Izumi
Yamazaki, Ayako
Ikota, Hayato
Oyama, Tetsunari
Ikeda, Yoshio
description The patient was a 70-year-old man with idiopathic orbital inflammation (IOI) that appeared on the severely affected side of preceding myasthenia gravis (MG). The patient was diagnosed with MG 5 years prior to the onset of IOI. When IOI was diagnosed, an edrophonium test was negative. IOI was considered because he complained of left orbital pain, eyelid swelling, and cerebral MRI exhibited the enhanced lesions along the left orbital periosteum. A biopsy specimen revealed pathological findings compatible with IOI. The administration of corticosteroids was effective for improving the ocular symptoms. IOI should be considered when ocular symptoms deteriorated with soft tissue swelling/pain in MG patients.
doi_str_mv 10.2169/internalmedicine.4235-19
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7434539</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2424444928</sourcerecordid><originalsourceid>FETCH-LOGICAL-c589t-f49dfa5f1dc4e07d3e10cfe35504441d6ded3c35974aa1a0cc029eec4604c3083</originalsourceid><addsrcrecordid>eNplkVFr2zAUhc3YWLNu_0Gwl724kyzJtl4GoaxdoCWDbY9D3EpXiYItZ5JS6L-fvITA2pcrLvrO0UGnqgijVw1r1WcfMsYAw4jWGx_wSjRc1ky9qhaMC1V3ZX1dLahifd2UcVG9S2lHKe871bytLnjTtkqydlH9Xlk_7SFvvSHr-OAzDGQV3ADjCNlPgSz3e4Tow4aUJW-RLJ1Dk9GSH94imRz5HtGUHIW4f4JUkOCB3EZ49Ol99cbBkPDD6bysft18_Xn9rb5b366ul3e1kb3KtRPKOpCOWSOQdpYjo8Yhl5IKIZhtLVpuuFSdAGBAjaGNQjSipcJw2vPL6svRd394KH9iMOQIg95HP0J80hN4_f9N8Fu9mR51J7iQXBWDTyeDOP05YMp69MngMEDA6ZB0I5qSRKhmfuvjM3Q3HeYy_lFKSsVFV6j-SJk4pRTRncMwqucO9fMO9dyhZnOW9VG6Sxk2eBZCzN4M-FIolWZinieHM2m2EDUG_hcNpbJ6</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2429559347</pqid></control><display><type>article</type><title>Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis</title><source>J-STAGE Free</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Fujita, Satoru ; Furuta, Natsumi ; Maruyama, Tokuzo ; Tsukagoshi, Setsuki ; Nagashima, Kazuaki ; Fujita, Yukio ; Nagai, Kazuki ; Kashima, Tomoyuki ; Tanaka, Makoto ; Miki, Izumi ; Yamazaki, Ayako ; Ikota, Hayato ; Oyama, Tetsunari ; Ikeda, Yoshio</creator><creatorcontrib>Fujita, Satoru ; Furuta, Natsumi ; Maruyama, Tokuzo ; Tsukagoshi, Setsuki ; Nagashima, Kazuaki ; Fujita, Yukio ; Nagai, Kazuki ; Kashima, Tomoyuki ; Tanaka, Makoto ; Miki, Izumi ; Yamazaki, Ayako ; Ikota, Hayato ; Oyama, Tetsunari ; Ikeda, Yoshio</creatorcontrib><description>The patient was a 70-year-old man with idiopathic orbital inflammation (IOI) that appeared on the severely affected side of preceding myasthenia gravis (MG). The patient was diagnosed with MG 5 years prior to the onset of IOI. When IOI was diagnosed, an edrophonium test was negative. IOI was considered because he complained of left orbital pain, eyelid swelling, and cerebral MRI exhibited the enhanced lesions along the left orbital periosteum. A biopsy specimen revealed pathological findings compatible with IOI. The administration of corticosteroids was effective for improving the ocular symptoms. IOI should be considered when ocular symptoms deteriorated with soft tissue swelling/pain in MG patients.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.4235-19</identifier><identifier>PMID: 32669516</identifier><language>eng</language><publisher>Tokyo: The Japanese Society of Internal Medicine</publisher><subject>Biopsy ; Case Report ; corticosteroid ; Corticosteroids ; Eyelid ; idiopathic orbital inflammation ; Internal medicine ; Magnetic resonance imaging ; Myasthenia ; Myasthenia gravis ; Neuromuscular junctions ; Pain ; Periosteum</subject><ispartof>Internal Medicine, 2020/07/15, Vol.59(14), pp.1763-1767</ispartof><rights>2020 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2020</rights><rights>Copyright © 2020 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c589t-f49dfa5f1dc4e07d3e10cfe35504441d6ded3c35974aa1a0cc029eec4604c3083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434539/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434539/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1877,27901,27902,53766,53768</link.rule.ids></links><search><creatorcontrib>Fujita, Satoru</creatorcontrib><creatorcontrib>Furuta, Natsumi</creatorcontrib><creatorcontrib>Maruyama, Tokuzo</creatorcontrib><creatorcontrib>Tsukagoshi, Setsuki</creatorcontrib><creatorcontrib>Nagashima, Kazuaki</creatorcontrib><creatorcontrib>Fujita, Yukio</creatorcontrib><creatorcontrib>Nagai, Kazuki</creatorcontrib><creatorcontrib>Kashima, Tomoyuki</creatorcontrib><creatorcontrib>Tanaka, Makoto</creatorcontrib><creatorcontrib>Miki, Izumi</creatorcontrib><creatorcontrib>Yamazaki, Ayako</creatorcontrib><creatorcontrib>Ikota, Hayato</creatorcontrib><creatorcontrib>Oyama, Tetsunari</creatorcontrib><creatorcontrib>Ikeda, Yoshio</creatorcontrib><title>Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>The patient was a 70-year-old man with idiopathic orbital inflammation (IOI) that appeared on the severely affected side of preceding myasthenia gravis (MG). The patient was diagnosed with MG 5 years prior to the onset of IOI. When IOI was diagnosed, an edrophonium test was negative. IOI was considered because he complained of left orbital pain, eyelid swelling, and cerebral MRI exhibited the enhanced lesions along the left orbital periosteum. A biopsy specimen revealed pathological findings compatible with IOI. The administration of corticosteroids was effective for improving the ocular symptoms. IOI should be considered when ocular symptoms deteriorated with soft tissue swelling/pain in MG patients.</description><subject>Biopsy</subject><subject>Case Report</subject><subject>corticosteroid</subject><subject>Corticosteroids</subject><subject>Eyelid</subject><subject>idiopathic orbital inflammation</subject><subject>Internal medicine</subject><subject>Magnetic resonance imaging</subject><subject>Myasthenia</subject><subject>Myasthenia gravis</subject><subject>Neuromuscular junctions</subject><subject>Pain</subject><subject>Periosteum</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNplkVFr2zAUhc3YWLNu_0Gwl724kyzJtl4GoaxdoCWDbY9D3EpXiYItZ5JS6L-fvITA2pcrLvrO0UGnqgijVw1r1WcfMsYAw4jWGx_wSjRc1ky9qhaMC1V3ZX1dLahifd2UcVG9S2lHKe871bytLnjTtkqydlH9Xlk_7SFvvSHr-OAzDGQV3ADjCNlPgSz3e4Tow4aUJW-RLJ1Dk9GSH94imRz5HtGUHIW4f4JUkOCB3EZ49Ol99cbBkPDD6bysft18_Xn9rb5b366ul3e1kb3KtRPKOpCOWSOQdpYjo8Yhl5IKIZhtLVpuuFSdAGBAjaGNQjSipcJw2vPL6svRd394KH9iMOQIg95HP0J80hN4_f9N8Fu9mR51J7iQXBWDTyeDOP05YMp69MngMEDA6ZB0I5qSRKhmfuvjM3Q3HeYy_lFKSsVFV6j-SJk4pRTRncMwqucO9fMO9dyhZnOW9VG6Sxk2eBZCzN4M-FIolWZinieHM2m2EDUG_hcNpbJ6</recordid><startdate>20200715</startdate><enddate>20200715</enddate><creator>Fujita, Satoru</creator><creator>Furuta, Natsumi</creator><creator>Maruyama, Tokuzo</creator><creator>Tsukagoshi, Setsuki</creator><creator>Nagashima, Kazuaki</creator><creator>Fujita, Yukio</creator><creator>Nagai, Kazuki</creator><creator>Kashima, Tomoyuki</creator><creator>Tanaka, Makoto</creator><creator>Miki, Izumi</creator><creator>Yamazaki, Ayako</creator><creator>Ikota, Hayato</creator><creator>Oyama, Tetsunari</creator><creator>Ikeda, Yoshio</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200715</creationdate><title>Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis</title><author>Fujita, Satoru ; Furuta, Natsumi ; Maruyama, Tokuzo ; Tsukagoshi, Setsuki ; Nagashima, Kazuaki ; Fujita, Yukio ; Nagai, Kazuki ; Kashima, Tomoyuki ; Tanaka, Makoto ; Miki, Izumi ; Yamazaki, Ayako ; Ikota, Hayato ; Oyama, Tetsunari ; Ikeda, Yoshio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c589t-f49dfa5f1dc4e07d3e10cfe35504441d6ded3c35974aa1a0cc029eec4604c3083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Biopsy</topic><topic>Case Report</topic><topic>corticosteroid</topic><topic>Corticosteroids</topic><topic>Eyelid</topic><topic>idiopathic orbital inflammation</topic><topic>Internal medicine</topic><topic>Magnetic resonance imaging</topic><topic>Myasthenia</topic><topic>Myasthenia gravis</topic><topic>Neuromuscular junctions</topic><topic>Pain</topic><topic>Periosteum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fujita, Satoru</creatorcontrib><creatorcontrib>Furuta, Natsumi</creatorcontrib><creatorcontrib>Maruyama, Tokuzo</creatorcontrib><creatorcontrib>Tsukagoshi, Setsuki</creatorcontrib><creatorcontrib>Nagashima, Kazuaki</creatorcontrib><creatorcontrib>Fujita, Yukio</creatorcontrib><creatorcontrib>Nagai, Kazuki</creatorcontrib><creatorcontrib>Kashima, Tomoyuki</creatorcontrib><creatorcontrib>Tanaka, Makoto</creatorcontrib><creatorcontrib>Miki, Izumi</creatorcontrib><creatorcontrib>Yamazaki, Ayako</creatorcontrib><creatorcontrib>Ikota, Hayato</creatorcontrib><creatorcontrib>Oyama, Tetsunari</creatorcontrib><creatorcontrib>Ikeda, Yoshio</creatorcontrib><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fujita, Satoru</au><au>Furuta, Natsumi</au><au>Maruyama, Tokuzo</au><au>Tsukagoshi, Setsuki</au><au>Nagashima, Kazuaki</au><au>Fujita, Yukio</au><au>Nagai, Kazuki</au><au>Kashima, Tomoyuki</au><au>Tanaka, Makoto</au><au>Miki, Izumi</au><au>Yamazaki, Ayako</au><au>Ikota, Hayato</au><au>Oyama, Tetsunari</au><au>Ikeda, Yoshio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2020-07-15</date><risdate>2020</risdate><volume>59</volume><issue>14</issue><spage>1763</spage><epage>1767</epage><pages>1763-1767</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>The patient was a 70-year-old man with idiopathic orbital inflammation (IOI) that appeared on the severely affected side of preceding myasthenia gravis (MG). The patient was diagnosed with MG 5 years prior to the onset of IOI. When IOI was diagnosed, an edrophonium test was negative. IOI was considered because he complained of left orbital pain, eyelid swelling, and cerebral MRI exhibited the enhanced lesions along the left orbital periosteum. A biopsy specimen revealed pathological findings compatible with IOI. The administration of corticosteroids was effective for improving the ocular symptoms. IOI should be considered when ocular symptoms deteriorated with soft tissue swelling/pain in MG patients.</abstract><cop>Tokyo</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>32669516</pmid><doi>10.2169/internalmedicine.4235-19</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0918-2918
ispartof Internal Medicine, 2020/07/15, Vol.59(14), pp.1763-1767
issn 0918-2918
1349-7235
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7434539
source J-STAGE Free; PubMed Central; PubMed Central Open Access
subjects Biopsy
Case Report
corticosteroid
Corticosteroids
Eyelid
idiopathic orbital inflammation
Internal medicine
Magnetic resonance imaging
Myasthenia
Myasthenia gravis
Neuromuscular junctions
Pain
Periosteum
title Idiopathic Orbital Inflammation Appearing on the Affected Side of Preceding Myasthenia Gravis
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T23%3A26%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Idiopathic%20Orbital%20Inflammation%20Appearing%20on%20the%20Affected%20Side%20of%20Preceding%20Myasthenia%20Gravis&rft.jtitle=Internal%20Medicine&rft.au=Fujita,%20Satoru&rft.date=2020-07-15&rft.volume=59&rft.issue=14&rft.spage=1763&rft.epage=1767&rft.pages=1763-1767&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.4235-19&rft_dat=%3Cproquest_pubme%3E2424444928%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2429559347&rft_id=info:pmid/32669516&rfr_iscdi=true