Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes Japanese encephalitis (JE), the most commonly diagnosed viral encephalitis worldwide. The fatality rate of JE is 20%, and nearly half of the surviving patients develop neuropsychiatric sequelae. Axl is a receptor tyrosine k...

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Veröffentlicht in:	Journal of virology 2020-08, Vol.94 (17)
Hauptverfasser:	Wang, Zhao-Yang, Zhen, Zi-Da, Fan, Dong-Ying, Qin, Cheng-Feng, Han, Dai-Shu, Zhou, Hong-Ning, Wang, Pei-Gang, An, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	Volltext
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