Diagnostic Value of a Modified Version of Wilson's Diagnostic Score in Pediatrics

Diagnostic Value of a Modified Version of Wilson's Diagnostic Score in Pediatrics

Background: Wilson's disease (WD) is an autosomal-recessive hereditary liver disease affecting copper metabolism. To test the diagnostic value of a questionnaire for the diagnosis of WD in pediatrics age group. 70 children with biopsy-proven diagnosis of WD and 70 without WD were included in th...

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Veröffentlicht in:International journal of organ transplantation medicine 2020, Vol.11 (2), p.65-70
Hauptverfasser: Sajedianfard, S, Ataollahi, M, Dehghani, S M
Format: Artikel
Sprache:eng
Schlagworte:
Age
Anemia
Biopsy
Developing countries
Hepatitis
Hepatology
Laboratories
LDCs
Liver diseases
Medical diagnosis
Metabolism
Mutation
Original
Pediatrics
Questionnaires
Regression analysis
Variables
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Zusammenfassung:Background: Wilson's disease (WD) is an autosomal-recessive hereditary liver disease affecting copper metabolism. To test the diagnostic value of a questionnaire for the diagnosis of WD in pediatrics age group. 70 children with biopsy-proven diagnosis of WD and 70 without WD were included in the study. A modified questionnaire with 4 items was used for the diagnosis of WD. The results were then compared to the definite diagnosis made by pathology (the gold standard test). The median (IQR) modified score in those with WD was 4 (4-5), significantly (p
ISSN:2008-6482
2008-6490