Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals

The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has affected more than eight million people. There is an urgent need to investigate how the adaptive immunity is established in COVID-19 patients. In this study, we profiled adaptive immune cells of PBMCs from recovered COV...

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Veröffentlicht in:	Signal transduction and targeted therapy 2020-08, Vol.5 (1), p.156-156, Article 156
Hauptverfasser:	Zhang, Fan, Gan, Rui, Zhen, Ziqi, Hu, Xiaoli, Li, Xiang, Zhou, Fengxia, Liu, Ying, Chen, Chuangeng, Xie, Shuangyu, Zhang, Bailing, Wu, Xiaoke, Huang, Zhiwei
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/2413 631/250/255 Adaptive immunity Antigens Antigens, Viral - genetics Antigens, Viral - immunology B-Lymphocytes - classification B-Lymphocytes - immunology B-Lymphocytes - virology Betacoronavirus - immunology Betacoronavirus - pathogenicity Cancer Research Case-Control Studies Cell Biology China Convalescence Coronavirus Infections - genetics Coronavirus Infections - immunology Coronavirus Infections - pathology Coronavirus Infections - virology Coronaviruses COVID-19 Disease Progression Gene Expression High-Throughput Nucleotide Sequencing Host-Pathogen Interactions - immunology Humans Immune response (humoral) Immunity, Cellular Immunity, Humoral Immunologic Memory Immunological memory Internal Medicine Lymphocytes B Lymphocytes T Medicine Medicine & Public Health Oncology Pandemics Pathology Pneumonia, Viral - genetics Pneumonia, Viral - immunology Pneumonia, Viral - pathology Pneumonia, Viral - virology Receptors, Antigen, B-Cell - classification Receptors, Antigen, B-Cell - genetics Receptors, Antigen, B-Cell - immunology Receptors, Antigen, T-Cell - classification Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Severity of Illness Index Single-Cell Analysis T cell receptors T-Lymphocytes - classification T-Lymphocytes - immunology T-Lymphocytes - virology
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