Ticagrelor Conditioning Effects Are Not Additive to Cardioprotection Induced by Direct NLRP3 Inflammasome Inhibition: Role of RISK, NLRP3, and Redox Cascades

Inhibition of either P2Y12 receptor or the nucleotide-binding oligomerization domain- (NOD-) like receptor pyrin domain containing 3 (NLRP3) inflammasome provides cardioprotective effects. Here, we investigate whether direct NLRP3 inflammasome inhibition exerts additive effects on myocardial protect...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2020, Vol.2020 (2020), p.1-12
Hauptverfasser:	Alves, Gustavo Ferreira, Zicola, Elisa, Mercurio, Valentina, Medana, Claudio, Collino, Massimo, Pagliaro, Pasquale, Collotta, Debora, Chiazza, Fausto, Bello, Federica Dal, Russo, Isabella, Femminò, Saveria, Cento, A. S., Aragno, Manuela, Penna, Claudia, Bertinaria, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Aggregation Animal experimentation Blood platelets Ethylenediaminetetraacetic acid Heart Ischemia Kinases Phosphatase Proteins Rodents
Online-Zugang:	Volltext
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