How should diagnostic kits development adapt quickly in COVID 19-like pandemic models? Pros and cons of sensory platforms used in COVID-19 sensing

As COVID-19 has reached pandemic status and the number of cases continues to grow, widespread availability of diagnostic testing is critical in helping identify and control the emergence of this rapidly spreading and serious illness. However, a lacking in making a quick reaction to the threat and st...

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Veröffentlicht in:Talanta (Oxford) 2021-01, Vol.222, p.121534-121534, Article 121534
Hauptverfasser: Moulahoum, Hichem, Ghorbanizamani, Faezeh, Zihnioglu, Figen, Turhan, Kutsal, Timur, Suna
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container_title Talanta (Oxford)
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creator Moulahoum, Hichem
Ghorbanizamani, Faezeh
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Turhan, Kutsal
Timur, Suna
description As COVID-19 has reached pandemic status and the number of cases continues to grow, widespread availability of diagnostic testing is critical in helping identify and control the emergence of this rapidly spreading and serious illness. However, a lacking in making a quick reaction to the threat and starting early development of diagnostic sensing tools has had an important impact globally. In this regard, here we will review critically the current developed diagnostic tools in response to the COVID-19 pandemic and compare the different types through the discussion of their pros and cons such as nucleic acid detection tests (including PCR and CRISPR), antibody and protein-based diagnosis tests. In addition, potential technologies that are under development such as on-site diagnosis platforms, lateral flow, and portable PCR units are discussed. Data collection and epidemiological analysis could also be an interesting factor to incorporate with the emerging technologies especially with the wide access to smartphones. Lastly, a SWOT analysis and perspectives on how the development of novel sensory platforms should be treated by the different decision-makers are analyzed. [Display omitted] •COVID 19 has become a major issue for society recently.•Developing performant diagnostic tools is crucial.•Many technologies have the potential to answer the needs for quick diagnostics.•On-site tools and smartphones needs more focus to stop viral spread.•A collaboration between law and decision makers is needed for better disease control.
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subjects Clinical Laboratory Techniques - instrumentation
Clinical Laboratory Techniques - methods
Coronavirus Infections - diagnosis
Coronavirus Infections - epidemiology
COVID-19
COVID-19 Testing
Diagnostic kits
Humans
Pandemics
Pneumonia, Viral - diagnosis
Pneumonia, Viral - epidemiology
Point-of-Care Testing
Reagent Kits, Diagnostic
Response strategies
Review
SARS-CoV-2
Sensors/biosensors
title How should diagnostic kits development adapt quickly in COVID 19-like pandemic models? Pros and cons of sensory platforms used in COVID-19 sensing
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