Obesity and CD8 T cell metabolism: Implications for anti‐tumor immunity and cancer immunotherapy outcomes

Obesity is an established risk factor for many cancers and has recently been found to alter the efficacy of T cell–based immunotherapies. Currently, however, the effects of obesity on immunometabolism remain unclear. Understanding these associations is critical, given the fact that T cell metabolism...

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Veröffentlicht in:Immunological reviews 2020-05, Vol.295 (1), p.203-219
Hauptverfasser: Turbitt, William J., Buchta Rosean, Claire, Weber, K. Scott, Norian, Lyse A.
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Sprache:eng
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