Direct synthesis of amides from nonactivated carboxylic acids using urea as nitrogen source and Mg(NO 3 ) 2 or imidazole as catalysts

A new method for the direct synthesis of primary and secondary amides from carboxylic acids is described using Mg(NO ) ·6H O or imidazole as a low-cost and readily available catalyst, and urea as a stable, and easy to manipulate nitrogen source. This methodology is particularly useful for the direct...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical science (Cambridge) 2020-06, Vol.11 (22), p.5808-5818
Hauptverfasser:	Chhatwal, A Rosie, Lomax, Helen V, Blacker, A John, Williams, Jonathan M J, Marcé, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Ammonia Carboxylic acids Catalysts Chemistry Coupling agents Imidazole Organic compounds Synthesis Ureas
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!