Passage of influenza A/H3N2 viruses in human airway cells removes artefactual variants associated with neuraminidase-mediated binding

Serological assays with modern influenza A/H3N2 viruses have become problematic due to the progressive reduction in the ability of viruses of this subtype to bind and agglutinate red blood cells (RBCs). This is due to reduced ability of the viral haemagglutinin (HA) glycoprotein to bind to the siali...

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Veröffentlicht in:Journal of general virology 2020-05, Vol.101 (5), p.456-466
Hauptverfasser: Brown, Jonathan C, Barclay, Wendy S, Galiano, Monica, Harvey, Ruth
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Sprache:eng
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