Effect of mandibular advancement device treatment on HIF-1α, EPO and VEGF in the myocardium of obstructive sleep apnea–hypopnea syndrome rabbits

The aim of this study was to investigate the effects of mandibular advancement device (MAD) therapy for obstructive sleep apnea–hypopnea syndrome (OSAHS) on hypoxia-inducible factor-1α (HIF-1α), erythropoietin (EPO) and vascular endothelial growth factor (VEGF) in myocardial tissue. New Zealand rabb...

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Veröffentlicht in:	Scientific reports 2020-08, Vol.10 (1), p.13261-13261, Article 13261
Hauptverfasser:	Zhu, Dechao, Kang, Wenjing, Zhang, Shilong, Qiao, Xing, Liu, Jie, Liu, Chunyan, Lu, Haiyan
Format:	Artikel
Sprache:	eng
Schlagworte:	692/1807 692/4019 692/420 692/499 692/53 692/698 692/699 Animals Apnea Case-Control Studies Computed tomography Cone-Beam Computed Tomography Disease Models, Animal Erythropoietin Erythropoietin - metabolism Humanities and Social Sciences Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Hypoxia-inducible factor 1a Male Mandible multidisciplinary Myocardium Myocardium - metabolism Occlusal Splints Polysomnography Rabbits Science Science (multidisciplinary) Sleep Sleep apnea Sleep Apnea, Obstructive - diagnostic imaging Sleep Apnea, Obstructive - metabolism Sleep Apnea, Obstructive - therapy Sleep disorders Up-Regulation Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
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