Emerging Roles of Inhibitor of Differentiation-1 in Alzheimer's Disease: Cell Cycle Reentry and Beyond

Inhibitor of DNA-binding/differentiation (Id) proteins, a family of helix-loop-helix (HLH) proteins that includes four members of Id1 to Id4 in mammalian cells, are critical for regulating cell growth, differentiation, senescence, cell cycle progression, and increasing angiogenesis and vasculogenesi...

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Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2020-07, Vol.9 (7), p.1746, Article 1746
Hauptverfasser:	Chen, Shang-Der, Yang, Jenq-Lin, Lin, Yi-Chun, Chao, A-Ching, Yang, Ding
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Angiogenesis Animals Apoptosis Cell adhesion & migration Cell Biology Cell Cycle cell cycle reentry Cell Death Cell differentiation Cell migration Cognitive ability Cyclin-dependent kinase 5 Cyclin-dependent kinases Deoxyribonucleic acid Disease DNA Gene expression Hedgehog protein Helix-loop-helix proteins Humans Hypoxia Hypoxia-inducible factor 1 Id1 protein Inhibitor of Differentiation Protein 1 - metabolism inhibitor of DNA-binding/differentiation proteins Kinases Life Sciences & Biomedicine Mammalian cells Mammals Models, Biological Nervous system Neuroblastoma Neurodegenerative diseases Neurogenesis Neurons Neurotoxicity Peptides Proteins Review Science & Technology Senescence Senile plaques Signal transduction Stem cells Therapeutic applications Transcription factors
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