Assessing the impact of coordinated COVID-19 exit strategies across Europe
As rates of new coronavirus disease 2019 (COVID-19) cases decline across Europe owing to nonpharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how to ease restrictions while minimizing the risk of resurgent outbreaks. We use mobility...
Gespeichert in:
| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2020-09, Vol.369 (6510), p.1465-1470 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1470 |
|---|---|
| container_issue | 6510 |
| container_start_page | 1465 |
| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 369 |
| creator | Ruktanonchai, N W Floyd, J R Lai, S Ruktanonchai, C W Sadilek, A Rente-Lourenco, P Ben, X Carioli, A Gwinn, J Steele, J E Prosper, O Schneider, A Oplinger, A Eastham, P Tatem, A J |
| description | As rates of new coronavirus disease 2019 (COVID-19) cases decline across Europe owing to nonpharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how to ease restrictions while minimizing the risk of resurgent outbreaks. We use mobility and case data to quantify how coordinated exit strategies could delay continental resurgence and limit community transmission of COVID-19. We find that a resurgent continental epidemic could occur as many as 5 weeks earlier when well-connected countries with stringent existing interventions end their interventions prematurely. Further, we find that appropriate coordination can greatly improve the likelihood of eliminating community transmission throughout Europe. In particular, synchronizing intermittent lockdowns across Europe means that half as many lockdown periods would be required to end continent-wide community transmission. |
| doi_str_mv | 10.1126/science.abc5096 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7402626</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2443914700</sourcerecordid><originalsourceid>FETCH-LOGICAL-c515t-e744d79f8babe7e831a8f76c70d82bb42f2027a604b1b28404e045a146b418953</originalsourceid><addsrcrecordid>eNpVkM1LAzEQxYMoWqtnbxLwvHWSzSbZiyD1m4IX9RqS7GyN2E1NtqL_vatW0dPAzJs3b36EHDCYMMblcfYBO48T63wFtdwgIwZ1VdQcyk0yAihloUFVO2Q35yeAYVaX22Sn5FKD1mxEbk5zxpxDN6f9I9KwWFrf09hSH2NqQmd7bOj09uH6rGA1xbfQ09ynoTsPmKn1KeZMz1cpLnGPbLX2OeP-uo7J_cX53fSqmN1eXk9PZ4WvWNUXqIRoVN1qZx0q1CWzulXSK2g0d07wlgNXVoJwzHEtQCCIyjIhnWC6rsoxOfn2Xa7cAhuP3RDo2SxTWNj0bqIN5v-kC49mHl-NEsAll4PB0dogxZcV5t48xVXqhsyGC1HWTKiB3Jgcf6u-fkzY_l5gYD7hmzV8s4Y_bBz-Dfar_6FdfgC5BYI6</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2443914700</pqid></control><display><type>article</type><title>Assessing the impact of coordinated COVID-19 exit strategies across Europe</title><source>MEDLINE</source><source>Science Magazine</source><creator>Ruktanonchai, N W ; Floyd, J R ; Lai, S ; Ruktanonchai, C W ; Sadilek, A ; Rente-Lourenco, P ; Ben, X ; Carioli, A ; Gwinn, J ; Steele, J E ; Prosper, O ; Schneider, A ; Oplinger, A ; Eastham, P ; Tatem, A J</creator><creatorcontrib>Ruktanonchai, N W ; Floyd, J R ; Lai, S ; Ruktanonchai, C W ; Sadilek, A ; Rente-Lourenco, P ; Ben, X ; Carioli, A ; Gwinn, J ; Steele, J E ; Prosper, O ; Schneider, A ; Oplinger, A ; Eastham, P ; Tatem, A J</creatorcontrib><description>As rates of new coronavirus disease 2019 (COVID-19) cases decline across Europe owing to nonpharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how to ease restrictions while minimizing the risk of resurgent outbreaks. We use mobility and case data to quantify how coordinated exit strategies could delay continental resurgence and limit community transmission of COVID-19. We find that a resurgent continental epidemic could occur as many as 5 weeks earlier when well-connected countries with stringent existing interventions end their interventions prematurely. Further, we find that appropriate coordination can greatly improve the likelihood of eliminating community transmission throughout Europe. In particular, synchronizing intermittent lockdowns across Europe means that half as many lockdown periods would be required to end continent-wide community transmission.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.abc5096</identifier><identifier>PMID: 32680881</identifier><language>eng</language><publisher>United States: The American Association for the Advancement of Science</publisher><subject>Community Relations ; Coordination ; Coronaviridae ; Coronavirus Infections - epidemiology ; Coronavirus Infections - prevention & control ; Coronavirus Infections - transmission ; Coronaviruses ; COVID-19 ; Disease control ; Disease transmission ; Epidemics ; Europe - epidemiology ; Humans ; Medicine ; Mobility ; Pandemics ; Pandemics - prevention & control ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - prevention & control ; Pneumonia, Viral - transmission ; Quarantine - methods ; Respiratory diseases ; Severe acute respiratory syndrome ; Severe acute respiratory syndrome coronavirus 2 ; Synchronism ; Travel - trends ; Viral diseases ; Viruses</subject><ispartof>Science (American Association for the Advancement of Science), 2020-09, Vol.369 (6510), p.1465-1470</ispartof><rights>Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.</rights><rights>Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works</rights><rights>Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). 2020 The Authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c515t-e744d79f8babe7e831a8f76c70d82bb42f2027a604b1b28404e045a146b418953</citedby><cites>FETCH-LOGICAL-c515t-e744d79f8babe7e831a8f76c70d82bb42f2027a604b1b28404e045a146b418953</cites><orcidid>0000-0001-9781-8148 ; 0000-0002-8345-5400 ; 0000-0001-7779-4695 ; 0000-0002-8042-0616 ; 0000-0003-0784-7098 ; 0000-0002-7270-941X ; 0000-0003-1546-4644 ; 0000-0001-6500-7121 ; 0000-0003-2022-0791 ; 0000-0003-4649-263X ; 0000-0001-6741-1195 ; 0000-0002-7889-3473</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,2871,2872,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32680881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ruktanonchai, N W</creatorcontrib><creatorcontrib>Floyd, J R</creatorcontrib><creatorcontrib>Lai, S</creatorcontrib><creatorcontrib>Ruktanonchai, C W</creatorcontrib><creatorcontrib>Sadilek, A</creatorcontrib><creatorcontrib>Rente-Lourenco, P</creatorcontrib><creatorcontrib>Ben, X</creatorcontrib><creatorcontrib>Carioli, A</creatorcontrib><creatorcontrib>Gwinn, J</creatorcontrib><creatorcontrib>Steele, J E</creatorcontrib><creatorcontrib>Prosper, O</creatorcontrib><creatorcontrib>Schneider, A</creatorcontrib><creatorcontrib>Oplinger, A</creatorcontrib><creatorcontrib>Eastham, P</creatorcontrib><creatorcontrib>Tatem, A J</creatorcontrib><title>Assessing the impact of coordinated COVID-19 exit strategies across Europe</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>As rates of new coronavirus disease 2019 (COVID-19) cases decline across Europe owing to nonpharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how to ease restrictions while minimizing the risk of resurgent outbreaks. We use mobility and case data to quantify how coordinated exit strategies could delay continental resurgence and limit community transmission of COVID-19. We find that a resurgent continental epidemic could occur as many as 5 weeks earlier when well-connected countries with stringent existing interventions end their interventions prematurely. Further, we find that appropriate coordination can greatly improve the likelihood of eliminating community transmission throughout Europe. In particular, synchronizing intermittent lockdowns across Europe means that half as many lockdown periods would be required to end continent-wide community transmission.</description><subject>Community Relations</subject><subject>Coordination</subject><subject>Coronaviridae</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - prevention & control</subject><subject>Coronavirus Infections - transmission</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Disease control</subject><subject>Disease transmission</subject><subject>Epidemics</subject><subject>Europe - epidemiology</subject><subject>Humans</subject><subject>Medicine</subject><subject>Mobility</subject><subject>Pandemics</subject><subject>Pandemics - prevention & control</subject><subject>Pneumonia, Viral - epidemiology</subject><subject>Pneumonia, Viral - prevention & control</subject><subject>Pneumonia, Viral - transmission</subject><subject>Quarantine - methods</subject><subject>Respiratory diseases</subject><subject>Severe acute respiratory syndrome</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Synchronism</subject><subject>Travel - trends</subject><subject>Viral diseases</subject><subject>Viruses</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM1LAzEQxYMoWqtnbxLwvHWSzSbZiyD1m4IX9RqS7GyN2E1NtqL_vatW0dPAzJs3b36EHDCYMMblcfYBO48T63wFtdwgIwZ1VdQcyk0yAihloUFVO2Q35yeAYVaX22Sn5FKD1mxEbk5zxpxDN6f9I9KwWFrf09hSH2NqQmd7bOj09uH6rGA1xbfQ09ynoTsPmKn1KeZMz1cpLnGPbLX2OeP-uo7J_cX53fSqmN1eXk9PZ4WvWNUXqIRoVN1qZx0q1CWzulXSK2g0d07wlgNXVoJwzHEtQCCIyjIhnWC6rsoxOfn2Xa7cAhuP3RDo2SxTWNj0bqIN5v-kC49mHl-NEsAll4PB0dogxZcV5t48xVXqhsyGC1HWTKiB3Jgcf6u-fkzY_l5gYD7hmzV8s4Y_bBz-Dfar_6FdfgC5BYI6</recordid><startdate>20200918</startdate><enddate>20200918</enddate><creator>Ruktanonchai, N W</creator><creator>Floyd, J R</creator><creator>Lai, S</creator><creator>Ruktanonchai, C W</creator><creator>Sadilek, A</creator><creator>Rente-Lourenco, P</creator><creator>Ben, X</creator><creator>Carioli, A</creator><creator>Gwinn, J</creator><creator>Steele, J E</creator><creator>Prosper, O</creator><creator>Schneider, A</creator><creator>Oplinger, A</creator><creator>Eastham, P</creator><creator>Tatem, A J</creator><general>The American Association for the Advancement of Science</general><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QQ</scope><scope>7QR</scope><scope>7SC</scope><scope>7SE</scope><scope>7SN</scope><scope>7SP</scope><scope>7SR</scope><scope>7SS</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7TM</scope><scope>7U5</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9781-8148</orcidid><orcidid>https://orcid.org/0000-0002-8345-5400</orcidid><orcidid>https://orcid.org/0000-0001-7779-4695</orcidid><orcidid>https://orcid.org/0000-0002-8042-0616</orcidid><orcidid>https://orcid.org/0000-0003-0784-7098</orcidid><orcidid>https://orcid.org/0000-0002-7270-941X</orcidid><orcidid>https://orcid.org/0000-0003-1546-4644</orcidid><orcidid>https://orcid.org/0000-0001-6500-7121</orcidid><orcidid>https://orcid.org/0000-0003-2022-0791</orcidid><orcidid>https://orcid.org/0000-0003-4649-263X</orcidid><orcidid>https://orcid.org/0000-0001-6741-1195</orcidid><orcidid>https://orcid.org/0000-0002-7889-3473</orcidid></search><sort><creationdate>20200918</creationdate><title>Assessing the impact of coordinated COVID-19 exit strategies across Europe</title><author>Ruktanonchai, N W ; Floyd, J R ; Lai, S ; Ruktanonchai, C W ; Sadilek, A ; Rente-Lourenco, P ; Ben, X ; Carioli, A ; Gwinn, J ; Steele, J E ; Prosper, O ; Schneider, A ; Oplinger, A ; Eastham, P ; Tatem, A J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c515t-e744d79f8babe7e831a8f76c70d82bb42f2027a604b1b28404e045a146b418953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Community Relations</topic><topic>Coordination</topic><topic>Coronaviridae</topic><topic>Coronavirus Infections - epidemiology</topic><topic>Coronavirus Infections - prevention & control</topic><topic>Coronavirus Infections - transmission</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Disease control</topic><topic>Disease transmission</topic><topic>Epidemics</topic><topic>Europe - epidemiology</topic><topic>Humans</topic><topic>Medicine</topic><topic>Mobility</topic><topic>Pandemics</topic><topic>Pandemics - prevention & control</topic><topic>Pneumonia, Viral - epidemiology</topic><topic>Pneumonia, Viral - prevention & control</topic><topic>Pneumonia, Viral - transmission</topic><topic>Quarantine - methods</topic><topic>Respiratory diseases</topic><topic>Severe acute respiratory syndrome</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Synchronism</topic><topic>Travel - trends</topic><topic>Viral diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ruktanonchai, N W</creatorcontrib><creatorcontrib>Floyd, J R</creatorcontrib><creatorcontrib>Lai, S</creatorcontrib><creatorcontrib>Ruktanonchai, C W</creatorcontrib><creatorcontrib>Sadilek, A</creatorcontrib><creatorcontrib>Rente-Lourenco, P</creatorcontrib><creatorcontrib>Ben, X</creatorcontrib><creatorcontrib>Carioli, A</creatorcontrib><creatorcontrib>Gwinn, J</creatorcontrib><creatorcontrib>Steele, J E</creatorcontrib><creatorcontrib>Prosper, O</creatorcontrib><creatorcontrib>Schneider, A</creatorcontrib><creatorcontrib>Oplinger, A</creatorcontrib><creatorcontrib>Eastham, P</creatorcontrib><creatorcontrib>Tatem, A J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Ecology Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ruktanonchai, N W</au><au>Floyd, J R</au><au>Lai, S</au><au>Ruktanonchai, C W</au><au>Sadilek, A</au><au>Rente-Lourenco, P</au><au>Ben, X</au><au>Carioli, A</au><au>Gwinn, J</au><au>Steele, J E</au><au>Prosper, O</au><au>Schneider, A</au><au>Oplinger, A</au><au>Eastham, P</au><au>Tatem, A J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessing the impact of coordinated COVID-19 exit strategies across Europe</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>2020-09-18</date><risdate>2020</risdate><volume>369</volume><issue>6510</issue><spage>1465</spage><epage>1470</epage><pages>1465-1470</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>As rates of new coronavirus disease 2019 (COVID-19) cases decline across Europe owing to nonpharmaceutical interventions such as social distancing policies and lockdown measures, countries require guidance on how to ease restrictions while minimizing the risk of resurgent outbreaks. We use mobility and case data to quantify how coordinated exit strategies could delay continental resurgence and limit community transmission of COVID-19. We find that a resurgent continental epidemic could occur as many as 5 weeks earlier when well-connected countries with stringent existing interventions end their interventions prematurely. Further, we find that appropriate coordination can greatly improve the likelihood of eliminating community transmission throughout Europe. In particular, synchronizing intermittent lockdowns across Europe means that half as many lockdown periods would be required to end continent-wide community transmission.</abstract><cop>United States</cop><pub>The American Association for the Advancement of Science</pub><pmid>32680881</pmid><doi>10.1126/science.abc5096</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-9781-8148</orcidid><orcidid>https://orcid.org/0000-0002-8345-5400</orcidid><orcidid>https://orcid.org/0000-0001-7779-4695</orcidid><orcidid>https://orcid.org/0000-0002-8042-0616</orcidid><orcidid>https://orcid.org/0000-0003-0784-7098</orcidid><orcidid>https://orcid.org/0000-0002-7270-941X</orcidid><orcidid>https://orcid.org/0000-0003-1546-4644</orcidid><orcidid>https://orcid.org/0000-0001-6500-7121</orcidid><orcidid>https://orcid.org/0000-0003-2022-0791</orcidid><orcidid>https://orcid.org/0000-0003-4649-263X</orcidid><orcidid>https://orcid.org/0000-0001-6741-1195</orcidid><orcidid>https://orcid.org/0000-0002-7889-3473</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 2020-09, Vol.369 (6510), p.1465-1470 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7402626 |
| source | MEDLINE; Science Magazine |
| subjects | Community Relations Coordination Coronaviridae Coronavirus Infections - epidemiology Coronavirus Infections - prevention & control Coronavirus Infections - transmission Coronaviruses COVID-19 Disease control Disease transmission Epidemics Europe - epidemiology Humans Medicine Mobility Pandemics Pandemics - prevention & control Pneumonia, Viral - epidemiology Pneumonia, Viral - prevention & control Pneumonia, Viral - transmission Quarantine - methods Respiratory diseases Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Synchronism Travel - trends Viral diseases Viruses |
| title | Assessing the impact of coordinated COVID-19 exit strategies across Europe |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T11%3A35%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessing%20the%20impact%20of%20coordinated%20COVID-19%20exit%20strategies%20across%20Europe&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Ruktanonchai,%20N%20W&rft.date=2020-09-18&rft.volume=369&rft.issue=6510&rft.spage=1465&rft.epage=1470&rft.pages=1465-1470&rft.issn=0036-8075&rft.eissn=1095-9203&rft_id=info:doi/10.1126/science.abc5096&rft_dat=%3Cproquest_pubme%3E2443914700%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2443914700&rft_id=info:pmid/32680881&rfr_iscdi=true |