A Feasibility Study of Drug–Drug Interaction Signal Detection in Regular Pharmacovigilance

Introduction Adverse drug reactions related to drug–drug interactions cause harm to patients. There is a body of research on signal detection for drug interactions in collections of individual case reports, but limited use in regular pharmacovigilance. Objective The aim of this study was to evaluate...

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Veröffentlicht in:	Drug safety 2020-08, Vol.43 (8), p.775-785
Hauptverfasser:	Hult, Sara, Sartori, Daniele, Bergvall, Tomas, Hedfors Vidlin, Sara, Grundmark, Birgitta, Ellenius, Johan, Norén, G. Niklas
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Case reports Collections Cytochrome Cytochrome P450 Cytochromes P450 Data mining Drug interaction Drug interactions Drug Safety and Pharmacovigilance Drugs Feasibility studies Filters Information sources Medicine Medicine & Public Health Natural language processing Original Original Research Article Pharmaceutical industry Pharmacokinetics Pharmacology Pharmacology/Toxicology Pharmacovigilance Prediction models Side effects Signal detection Statistical methods Statistics
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