Sub-residue Resolution Footprinting of Ligand-Protein Interactions by Carbene Chemistry and Ion Mobility-Mass Spectrometry

The knowledge of ligand-protein interactions is essential for understanding fundamental biological processes and for the rational design of drugs that target such processes. Carbene footprinting efficiently labels proteinaceous residues, and has been used with mass spectrometry (MS) to map ligand-pr...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-12, Vol.92 (1), p.947-956
Hauptverfasser:	Lu, Gaoyuan, Xu, Xiaowei, Li, Gongyu, Sun, Huiyong, Wang, Nian, Zhu, Yinxue, Wan, Ning, Shi, Yatao, Wang, Guangji, Li, Lingjun, Hao, Haiping, Ye, Hui
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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