Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: polyelectrolyte complexes vs. amphiphilic nanoassemblies

Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respectively, which offered distinct enzyme-triggere...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-07, Vol.56 (60), p.8456-8459
Hauptverfasser: Kumar, Vikash, Munkhbat, Oyuntuya, Secinti, Hatice, Thayumanavan, S
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creator Kumar, Vikash
Munkhbat, Oyuntuya
Secinti, Hatice
Thayumanavan, S
description Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respectively, which offered distinct enzyme-triggered disassembly kinetics.
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Alkaline phosphatase
Alkaline Phosphatase - metabolism
Dismantling
Enzymes
Hydrophobic and Hydrophilic Interactions
Kinetics
Nanoparticles
Nanoparticles - chemistry
Polyelectrolytes
Polyelectrolytes - chemistry
Polyelectrolytes - metabolism
Polymers
Polymers - chemistry
Polymers - metabolism
title Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: polyelectrolyte complexes vs. amphiphilic nanoassemblies
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