miR‑187‑3p inhibitor attenuates cerebral ischemia/reperfusion injury by regulating Seipin‑mediated autophagic flux

MicroRNAs (miRNAs/miRs) have been reported to affect ischemia/reperfusion (I/R)-induced cerebral damage. miRNAs cause post-transcriptional gene silencing by binding to the protein-coding sequence (CDS) of mRNAs. Seipin has a potential role in regulating autophagic flux. The present study investigate...

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Veröffentlicht in:	International journal of molecular medicine 2020-09, Vol.46 (3), p.1051-1062
Hauptverfasser:	Ren, Zhenkui, Xie, Peng, Lv, Ju, Hu, Yumei, Guan, Zhizhong, Chen, Ling, Yu, Wenfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Autophagy Binding sites Biotechnology Brain Cloning Experiments Genetic aspects Genetic engineering Glucose Ischemia MicroRNA MicroRNAs Microscopy Pharmaceutical industry Protein binding Proteins Reagents Scientific equipment industry Transcription (Genetics)
Online-Zugang:	Volltext
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