Absent immune response to SARS-CoV-2 in a 3-month recurrence of coronavirus disease 2019 (COVID-19) case

Background The viral persistence in patients with Coronavirus Disease 2019 (COVID-19) remains to be investigated. Methods We investigated the viral loads, therapies, clinical features, and immune responses in a 70-year patient tested positive for SARS-CoV-2 for 3 months. Findings The patient exhibit...

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Veröffentlicht in:	Infection 2021-02, Vol.49 (1), p.57-61
Hauptverfasser:	Gao, Guosheng, Zhu, Zhe, Fan, Lingyan, Ye, Shuyuan, Huang, Zuoan, Shi, Qiaoyun, Sun, Yedan, Song, Qifa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antiviral Agents - therapeutic use Biomarkers - blood C-reactive protein C-Reactive Protein - immunology C-Reactive Protein - metabolism Computed tomography Coronaviruses COVID-19 COVID-19 - diagnostic imaging COVID-19 - immunology COVID-19 - pathology COVID-19 - virology COVID-19 Testing - methods Creatinine Creatinine - blood Creatinine - immunology Exudation Family Medicine Fever Fever - diagnostic imaging Fever - immunology Fever - pathology Fever - virology General Practice Hospitalization Humans Immune response Immune system Immunity Infectious Diseases Interferon-gamma - blood Interferon-gamma - immunology Interleukin 10 Interleukin 2 Interleukin 6 Interleukin-10 - blood Interleukin-10 - immunology Interleukin-2 - blood Interleukin-2 - immunology Interleukin-6 - blood Interleukin-6 - immunology Internal Medicine Lymphocytes Lymphopenia - diagnostic imaging Lymphopenia - immunology Lymphopenia - pathology Lymphopenia - virology Male Medicine Medicine & Public Health N gene Original Paper Polymerase chain reaction Recurrence Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 SARS-CoV-2 - genetics SARS-CoV-2 - immunology SARS-CoV-2 - pathogenicity Severe acute respiratory syndrome coronavirus 2 Tomography, X-Ray Computed Tumor Necrosis Factor-alpha - blood Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-α Urea Viral diseases Viral Load - drug effects Virus Shedding - immunology γ-Interferon
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