Two distinct nucleic acid binding surfaces of Cdc5 regulate development

Cell division cycle 5 (Cdc5) is a highly conserved nucleic acid binding protein among eukaryotes and plays critical roles in development. Cdc5 can simultaneously bind to DNA and RNA by its N-terminal DNA-binding domain (DBD), but molecular mechanisms describing its nucleic acid recognition and the r...

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Veröffentlicht in:Biochemical journal 2019-11, Vol.476 (21), p.3355-3368
Hauptverfasser: Wang, Chao, Li, Mu, Li, Guorui, Liu, Xinsen, Zhao, Wensheng, Yu, Bin, Liu, Junfeng, Yang, Jun, Peng, You-Liang
Format: Artikel
Sprache:eng
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