Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis
Aims. The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A computerized search was performed to determine the rel...
Gespeichert in:
| Veröffentlicht in: | Contrast media and molecular imaging 2020, Vol.2020 (2020), p.1-11 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 11 |
|---|---|
| container_issue | 2020 |
| container_start_page | 1 |
| container_title | Contrast media and molecular imaging |
| container_volume | 2020 |
| creator | Dahmarde, Hamid Salarzaei, Morteza Parooie, Fateme |
| description | Aims. The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis. Results. the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUVmax cut-off value (≤2.5) demonstrated the best accuracy. Conclusion. 18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer. |
| doi_str_mv | 10.1155/2020/5439378 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7383332</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2429776845</sourcerecordid><originalsourceid>FETCH-LOGICAL-e2838-a152a5c204669a5bf68dda997f6f2657beedf5bd9fa391c29ee2744cc187bac73</originalsourceid><addsrcrecordid>eNpd0c-L1DAUB_Aiiruu3jxLwIsgdZpfTeNhYejurAvjD3TEY3hNX50sbTM27S49-L-b2RlWFAIJyed9SfKS5CXN3lEq5YJlLFtIwTVXxaPkNG7JVHCqHj-sM32SPAvhJsvEnj1NTjhTPBJxmvy-DoQWq3R1cUW-XG4W5YZAT5bWTgOMSH7ATEZPLnBEO5L13O225JOvkXzEEUIcLhDXk9K3fogCWlJCb3F4T5bk2xxG7GB0lnzFW4d3Mbm-L0yXPbRzrH2ePGmgDfjiOJ8l31eXm_JDuv58dV0u1ymyghcpUMlAWpaJPNcgqyYv6hq0Vk3esFyqCrFuZFXrBrimlmlEpoSwlhaqAqv4WXJ-yN1NVYe1xX4coDW7wXUwzMaDM_-e9G5rfvpbo3jBOWcx4M0xYPC_Jgyj6Vyw2LbQo5-CYYJppfJCyEhf_0dv_DTEB98rxRhXWkf19qC2rq_hzj3chWZm31azb6s5tjXqVwcd_3PABv5qyjXLc_4HFVibvw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2427223799</pqid></control><display><type>article</type><title>Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis</title><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>Dahmarde, Hamid ; Salarzaei, Morteza ; Parooie, Fateme</creator><contributor>Palumbo, Barbara ; Barbara Palumbo</contributor><creatorcontrib>Dahmarde, Hamid ; Salarzaei, Morteza ; Parooie, Fateme ; Palumbo, Barbara ; Barbara Palumbo</creatorcontrib><description>Aims. The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis. Results. the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUVmax cut-off value (≤2.5) demonstrated the best accuracy. Conclusion. 18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer.</description><identifier>ISSN: 1555-4309</identifier><identifier>EISSN: 1555-4317</identifier><identifier>DOI: 10.1155/2020/5439378</identifier><identifier>PMID: 32733174</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Asymmetry ; Bias ; Cancer ; Colorectal cancer ; Colorectal carcinoma ; Computed tomography ; Diagnostic systems ; Emission analysis ; Fluorine isotopes ; Histopathology ; Likelihood ratio ; Lymph nodes ; Lymphatic system ; Magnetic resonance imaging ; Medical prognosis ; Meta-analysis ; Metastases ; Metastasis ; Positron emission ; Positron emission tomography ; Sensitivity analysis ; Studies ; Systematic review ; Tomography</subject><ispartof>Contrast media and molecular imaging, 2020, Vol.2020 (2020), p.1-11</ispartof><rights>Copyright © 2020 Hamid Dahmarde et al.</rights><rights>Copyright © 2020 Hamid Dahmarde et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. http://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2020 Hamid Dahmarde et al. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0001-5508-8669</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383332/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383332/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,4010,27900,27901,27902,53766,53768</link.rule.ids></links><search><contributor>Palumbo, Barbara</contributor><contributor>Barbara Palumbo</contributor><creatorcontrib>Dahmarde, Hamid</creatorcontrib><creatorcontrib>Salarzaei, Morteza</creatorcontrib><creatorcontrib>Parooie, Fateme</creatorcontrib><title>Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis</title><title>Contrast media and molecular imaging</title><description>Aims. The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis. Results. the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUVmax cut-off value (≤2.5) demonstrated the best accuracy. Conclusion. 18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer.</description><subject>Asymmetry</subject><subject>Bias</subject><subject>Cancer</subject><subject>Colorectal cancer</subject><subject>Colorectal carcinoma</subject><subject>Computed tomography</subject><subject>Diagnostic systems</subject><subject>Emission analysis</subject><subject>Fluorine isotopes</subject><subject>Histopathology</subject><subject>Likelihood ratio</subject><subject>Lymph nodes</subject><subject>Lymphatic system</subject><subject>Magnetic resonance imaging</subject><subject>Medical prognosis</subject><subject>Meta-analysis</subject><subject>Metastases</subject><subject>Metastasis</subject><subject>Positron emission</subject><subject>Positron emission tomography</subject><subject>Sensitivity analysis</subject><subject>Studies</subject><subject>Systematic review</subject><subject>Tomography</subject><issn>1555-4309</issn><issn>1555-4317</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>BENPR</sourceid><recordid>eNpd0c-L1DAUB_Aiiruu3jxLwIsgdZpfTeNhYejurAvjD3TEY3hNX50sbTM27S49-L-b2RlWFAIJyed9SfKS5CXN3lEq5YJlLFtIwTVXxaPkNG7JVHCqHj-sM32SPAvhJsvEnj1NTjhTPBJxmvy-DoQWq3R1cUW-XG4W5YZAT5bWTgOMSH7ATEZPLnBEO5L13O225JOvkXzEEUIcLhDXk9K3fogCWlJCb3F4T5bk2xxG7GB0lnzFW4d3Mbm-L0yXPbRzrH2ePGmgDfjiOJ8l31eXm_JDuv58dV0u1ymyghcpUMlAWpaJPNcgqyYv6hq0Vk3esFyqCrFuZFXrBrimlmlEpoSwlhaqAqv4WXJ-yN1NVYe1xX4coDW7wXUwzMaDM_-e9G5rfvpbo3jBOWcx4M0xYPC_Jgyj6Vyw2LbQo5-CYYJppfJCyEhf_0dv_DTEB98rxRhXWkf19qC2rq_hzj3chWZm31azb6s5tjXqVwcd_3PABv5qyjXLc_4HFVibvw</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Dahmarde, Hamid</creator><creator>Salarzaei, Morteza</creator><creator>Parooie, Fateme</creator><general>Hindawi Publishing Corporation</general><general>Hindawi</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5508-8669</orcidid></search><sort><creationdate>2020</creationdate><title>Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis</title><author>Dahmarde, Hamid ; Salarzaei, Morteza ; Parooie, Fateme</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e2838-a152a5c204669a5bf68dda997f6f2657beedf5bd9fa391c29ee2744cc187bac73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Asymmetry</topic><topic>Bias</topic><topic>Cancer</topic><topic>Colorectal cancer</topic><topic>Colorectal carcinoma</topic><topic>Computed tomography</topic><topic>Diagnostic systems</topic><topic>Emission analysis</topic><topic>Fluorine isotopes</topic><topic>Histopathology</topic><topic>Likelihood ratio</topic><topic>Lymph nodes</topic><topic>Lymphatic system</topic><topic>Magnetic resonance imaging</topic><topic>Medical prognosis</topic><topic>Meta-analysis</topic><topic>Metastases</topic><topic>Metastasis</topic><topic>Positron emission</topic><topic>Positron emission tomography</topic><topic>Sensitivity analysis</topic><topic>Studies</topic><topic>Systematic review</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dahmarde, Hamid</creatorcontrib><creatorcontrib>Salarzaei, Morteza</creatorcontrib><creatorcontrib>Parooie, Fateme</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access Journals</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Contrast media and molecular imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dahmarde, Hamid</au><au>Salarzaei, Morteza</au><au>Parooie, Fateme</au><au>Palumbo, Barbara</au><au>Barbara Palumbo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis</atitle><jtitle>Contrast media and molecular imaging</jtitle><date>2020</date><risdate>2020</risdate><volume>2020</volume><issue>2020</issue><spage>1</spage><epage>11</epage><pages>1-11</pages><issn>1555-4309</issn><eissn>1555-4317</eissn><abstract>Aims. The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. Material and Methods. A computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis. Results. the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUVmax cut-off value (≤2.5) demonstrated the best accuracy. Conclusion. 18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>32733174</pmid><doi>10.1155/2020/5439378</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-5508-8669</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1555-4309 |
| ispartof | Contrast media and molecular imaging, 2020, Vol.2020 (2020), p.1-11 |
| issn | 1555-4309 1555-4317 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7383332 |
| source | PubMed Central; Alma/SFX Local Collection; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Asymmetry Bias Cancer Colorectal cancer Colorectal carcinoma Computed tomography Diagnostic systems Emission analysis Fluorine isotopes Histopathology Likelihood ratio Lymph nodes Lymphatic system Magnetic resonance imaging Medical prognosis Meta-analysis Metastases Metastasis Positron emission Positron emission tomography Sensitivity analysis Studies Systematic review Tomography |
| title | Is 18F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T11%3A12%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Is%2018F-FDG%20PET/CT%20an%20Accurate%20Way%20to%20Detect%20Lymph%20Node%20Metastasis%20in%20Colorectal%20Cancer:%20A%20Systematic%20Review%20and%20Meta-Analysis&rft.jtitle=Contrast%20media%20and%20molecular%20imaging&rft.au=Dahmarde,%20Hamid&rft.date=2020&rft.volume=2020&rft.issue=2020&rft.spage=1&rft.epage=11&rft.pages=1-11&rft.issn=1555-4309&rft.eissn=1555-4317&rft_id=info:doi/10.1155/2020/5439378&rft_dat=%3Cproquest_pubme%3E2429776845%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2427223799&rft_id=info:pmid/32733174&rfr_iscdi=true |