Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF‐κB activity

Tracheitis secondary to placement of an endotracheal tube (ETT) is characterized by neutrophil accumulation in the tracheal lumen, which is generally associated with epithelial damage. Mitochondrial DNA (mtDNA), has been implicated in systemic inflammation and organ dysfunction following trauma; how...

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Veröffentlicht in:	Journal of leukocyte biology 2019-03, Vol.105 (3), p.577-587
Hauptverfasser:	Puyo, Carlos A., Earhart, Alexander, Staten, Nicholas, Prince, Oliver A., Haug, Colleen, Kollef, Marin, Awad, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	endotracheal intubation mitochondrial DNA neutrophils pain TLRs Translational & Clinical Immunology
Online-Zugang:	Volltext
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