Colchicine Alleviates Cholesterol Crystal-Induced Endothelial Cell Pyroptosis through Activating AMPK/SIRT1 Pathway

Cholesterol crystal- (CC-) induced endothelial cell inflammation and pyroptosis play an important role in the development of cardiovascular diseases, especially in atherosclerosis (AS). Increasing evidence suggests that cholesterol crystals are known to be a pivotal pathological marker of atheroscle...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oxidative medicine and cellular longevity 2020, Vol.2020 (2020), p.1-18, Article 9173530
Hauptverfasser:	Liu, Dandan, Wang, Gang, Hou, Jingbo, Yu, Bo, Han, Baihe, Wang, Xuedong, Huang, Xingtao, Zhang, Ruoxi, Zhang, Lu, Liu, Qi, Lv, Hang, Yang, Mengyue, Hou, Shenglong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes AMP-Activated Protein Kinases - metabolism Apoptosis Atherosclerosis Biotechnology Cardiovascular disease Cardiovascular diseases Cell Biology Cholesterol Colchicine Colchicine - pharmacology Colchicine - therapeutic use Cytotoxicity Endothelium Enzymes Heart attacks Humans Inflammation Laboratories Life Sciences & Biomedicine Lipid peroxidation Lipids Oxidative stress Proteins Pyroptosis - drug effects Reactive Oxygen Species - metabolism Science & Technology Sirtuin 1 - metabolism Transfection Tubulin Modulators - pharmacology Tubulin Modulators - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!