Circuit Design Features of a Stable Two-Cell System

Cell communication within tissues is mediated by multiple paracrine signals including growth factors, which control cell survival and proliferation. Cells and the growth factors they produce and receive constitute a circuit with specific properties that ensure homeostasis. Here, we used computationa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell 2018-02, Vol.172 (4), p.744-757.e17
Hauptverfasser:	Zhou, Xu, Franklin, Ruth A., Adler, Miri, Jacox, Jeremy B., Bailis, Will, Shyer, Justin A., Flavell, Richard A., Mayo, Avi, Alon, Uri, Medzhitov, Ruslan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals carrying capacity cell circuits Cell Communication - physiology Cell Proliferation - physiology Cell Survival - physiology cell-cell contact CSF1 Female fibroblasts Fibroblasts - cytology Fibroblasts - metabolism growth factors macrophages Macrophages - cytology Macrophages - metabolism Male Mice Mice, Transgenic PDGF stability tissue homeostasis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!