The C-Terminus and Third Cytoplasmic Loop Cooperatively Activate Mouse Melanopsin Phototransduction

Melanopsin, an atypical vertebrate visual pigment, mediates non-image-forming light responses including circadian photoentrainment and pupillary light reflexes and contrast detection for image formation. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells are characterized by s...

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Veröffentlicht in:	Biophysical journal 2020-07, Vol.119 (2), p.389-401
Hauptverfasser:	Valdez-Lopez, Juan C., Petr, Stephen T., Donohue, Matthew P., Bailey, Robin J., Gebreeziabher, Meheret, Cameron, Evan G., Wolf, Julia B., Szalai, Veronika A., Robinson, Phyllis R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Light Light Signal Transduction Mice Phosphorylation Retinal Ganglion Cells - metabolism Rod Opsins - genetics Rod Opsins - metabolism
Online-Zugang:	Volltext
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