Molecular and nanoscale evaluation of N-cadherin expression in invasive bladder cancer cells under control conditions or GW501516 exposure

N-cadherin is a transmembrane glycoprotein expressed by mesenchymal origin cells and is located at the adherens junctions. It regulates also cell motility and contributes to cell signaling. In previous studies, we identified that its anomalous expression in bladder carcinoma was a tumor progression...

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Veröffentlicht in:	Molecular and cellular biochemistry 2020-08, Vol.471 (1-2), p.113-127
Hauptverfasser:	Elie-Caille, Céline, Lascombe, Isabelle, Péchery, Adeline, Bittard, Hugues, Fauconnet, Sylvie
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustics Adherens junctions Antibodies Antigens, CD - metabolism Antigens, CD - ultrastructure Atomic force microscopy Biochemistry Biomedical and Life Sciences Bladder Bladder cancer Cadherins - metabolism Cadherins - ultrastructure Cancer Cancer cells Cardiology Cell Line, Tumor Cell Movement Cell spreading Cell surface Confocal microscopy Cytology Cytotoxicity Engineering Sciences Epithelial-Mesenchymal Transition Ethylenediaminetetraacetic acid Glycoproteins Humans Invasiveness Life Sciences Materials Medical Biochemistry Mesenchyme Metastases Metastasis Micro and nanotechnologies Microelectronics Microscopy Microscopy, Atomic Force - methods Molecular biology Morphology N-Cadherin Oncology PPAR delta - agonists PPAR-beta - agonists Signal Transduction Spectroscopy Thiazoles - pharmacology Urinary Bladder Neoplasms - drug therapy Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - ultrastructure Viral antibodies Western blotting Wound healing
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