GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

Carnosine and related β-alanine-containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This study describes the first animal model lacking the enzyme glutamic acid decarboxy...

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Veröffentlicht in:	Science advances 2020-07, Vol.6 (29), p.eabb3713
Hauptverfasser:	Mahootchi, Elaheh, Cannon Homaei, Selina, Kleppe, Rune, Winge, Ingeborg, Hegvik, Tor-Arne, Megias-Perez, Roberto, Totland, Christian, Mogavero, Floriana, Baumann, Anne, Glennon, Jeffrey Colm, Miletic, Hrvoje, Kursula, Petri, Haavik, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Neuroscience SciAdv r-articles
Online-Zugang:	Volltext
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