Preliminary results in the analysis of the immune response after aneurysmal subarachnoid hemorrhage

Cerebral vasospasm (VSP) is a common phenomenon after aneurysmal subarachnoid hemorrhage (aSAH) and contributes to neurocognitive decline. The natural history of the pro-inflammatory immune response after aSAH has not been prospectively studied in human cerebrospinal fluid (CSF). In this pilot study...

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Veröffentlicht in:	Scientific reports 2020-07, Vol.10 (1), p.11809-11809, Article 11809
Hauptverfasser:	Roa, Jorge A., Sarkar, Deepon, Zanaty, Mario, Ishii, Daizo, Lu, Yongjun, Karandikar, Nitin J., Hasan, David M., Ortega, Sterling B., Samaniego, Edgar A.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250 631/250/127 631/250/2152 631/250/2504 631/250/256 631/250/262 631/250/98 692/617 692/617/375 Adaptive Immunity Adult Aged Aged, 80 and over Aneurysm Aneurysm, Ruptured - complications Aneurysms Angiography Biomarkers CD3 antigen CD45 antigen CD8 antigen Cerebrospinal fluid Cognition Computed tomography Cytokines - metabolism Enzyme-linked immunosorbent assay Female Flow cytometry Gelatinase B Hemorrhage Humanities and Social Sciences Humans Immune response Immunity Immunity, Innate Immunohistochemistry Inflammation Inflammation Mediators Lymphocytes Male Microglia Middle Aged multidisciplinary Neuroimaging Perfusion Peripheral blood Science Science (multidisciplinary) Stroke Subarachnoid hemorrhage Subarachnoid Hemorrhage - etiology Subarachnoid Hemorrhage - metabolism Subarachnoid Hemorrhage - pathology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocyte Subsets - pathology Variance analysis Vascular endothelial growth factor Vasoconstriction Vasospasm, Intracranial - etiology Vasospasm, Intracranial - metabolism
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