Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report
COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID...
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Veröffentlicht in: | Journal of clinical neuroscience 2020-09, Vol.79, p.169-171 |
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description | COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management. |
doi_str_mv | 10.1016/j.jocn.2020.07.034 |
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The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management.</description><identifier>ISSN: 0967-5868</identifier><identifier>EISSN: 1532-2653</identifier><identifier>DOI: 10.1016/j.jocn.2020.07.034</identifier><identifier>PMID: 33070890</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Adult ; Betacoronavirus ; Case Report ; Coronavirus Infections - complications ; COVID-19 ; Humans ; Magnetic Resonance Imaging ; Male ; Multimodal Imaging ; Pandemics ; Pneumonia, Viral - complications ; SARS-CoV-2 ; Stroke ; Stroke - diagnostic imaging ; Stroke - etiology ; Tomography, X-Ray Computed ; Vasculitis ; Vasculitis - diagnostic imaging ; Vasculitis - etiology</subject><ispartof>Journal of clinical neuroscience, 2020-09, Vol.79, p.169-171</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><rights>2020 Elsevier Ltd. All rights reserved. 2020 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-4cf8a902ca4cc4b3ec5c1908adf437b4f96eb736763926847dae8d5deef910df3</citedby><cites>FETCH-LOGICAL-c422t-4cf8a902ca4cc4b3ec5c1908adf437b4f96eb736763926847dae8d5deef910df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0967586820313722$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33070890$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Sousa, Gustavo Celeira</creatorcontrib><creatorcontrib>de Sousa, Thiago Celeira</creatorcontrib><creatorcontrib>Sakiyama, Marcelo Akira Kobayashi</creatorcontrib><creatorcontrib>da Silva, Jeanne Seabra Negrão Lima</creatorcontrib><creatorcontrib>de Sousa, Emanuel de Jesus Soares</creatorcontrib><title>Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report</title><title>Journal of clinical neuroscience</title><addtitle>J Clin Neurosci</addtitle><description>COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management.</description><subject>Adult</subject><subject>Betacoronavirus</subject><subject>Case Report</subject><subject>Coronavirus Infections - complications</subject><subject>COVID-19</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Multimodal Imaging</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - complications</subject><subject>SARS-CoV-2</subject><subject>Stroke</subject><subject>Stroke - diagnostic imaging</subject><subject>Stroke - etiology</subject><subject>Tomography, X-Ray Computed</subject><subject>Vasculitis</subject><subject>Vasculitis - diagnostic imaging</subject><subject>Vasculitis - etiology</subject><issn>0967-5868</issn><issn>1532-2653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1OHDEQha0IFAaSC2SBvCSLbqpt94-lKFI04U9Cmg2ZreWxy-BJ057Y3SOx4w7cMCehW5Mg2LCyyn7vK1c9Qr4UkBdQVKfrfB1MlzNgkEOdAxcfyKwoOctYVfI9MgNZ1VnZVM0BOUxpDQBScPhIDjiHGhoJM_JnqZMZWt_7lEVsdY-Wpj6G30h9Rx_C0N1Snaimm4gJu96PtUPdDxFpcLQLW2ypCTF0euvjkKj1CXVCejJfLK9-FvIr_fv4ROfTVcRNiP0nsu90m_Dzv_OI_Do_u5lfZteLi6v5j-vMCMb6TBjXaAnMaGGMWHE0pSkkNNo6weuVcLLCVc2ruuKSVY2orcbGlhbRyQKs40fk-467GVb3aM34-ahbtYn-XscHFbRXb186f6duw1ZN0HFVI4DtACaGlCK6F28BagpArdUUgJoCUFCrMYDRdPy664vl_8ZHwbedAMfZtx6jSsZjZ9D6iKZXNvj3-M-POZsW</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>de Sousa, Gustavo Celeira</creator><creator>de Sousa, Thiago Celeira</creator><creator>Sakiyama, Marcelo Akira Kobayashi</creator><creator>da Silva, Jeanne Seabra Negrão Lima</creator><creator>de Sousa, Emanuel de Jesus Soares</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20200901</creationdate><title>Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report</title><author>de Sousa, Gustavo Celeira ; de Sousa, Thiago Celeira ; Sakiyama, Marcelo Akira Kobayashi ; da Silva, Jeanne Seabra Negrão Lima ; de Sousa, Emanuel de Jesus Soares</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-4cf8a902ca4cc4b3ec5c1908adf437b4f96eb736763926847dae8d5deef910df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Betacoronavirus</topic><topic>Case Report</topic><topic>Coronavirus Infections - complications</topic><topic>COVID-19</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Multimodal Imaging</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - complications</topic><topic>SARS-CoV-2</topic><topic>Stroke</topic><topic>Stroke - diagnostic imaging</topic><topic>Stroke - etiology</topic><topic>Tomography, X-Ray Computed</topic><topic>Vasculitis</topic><topic>Vasculitis - diagnostic imaging</topic><topic>Vasculitis - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Sousa, Gustavo Celeira</creatorcontrib><creatorcontrib>de Sousa, Thiago Celeira</creatorcontrib><creatorcontrib>Sakiyama, Marcelo Akira Kobayashi</creatorcontrib><creatorcontrib>da Silva, Jeanne Seabra Negrão Lima</creatorcontrib><creatorcontrib>de Sousa, Emanuel de Jesus Soares</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Sousa, Gustavo Celeira</au><au>de Sousa, Thiago Celeira</au><au>Sakiyama, Marcelo Akira Kobayashi</au><au>da Silva, Jeanne Seabra Negrão Lima</au><au>de Sousa, Emanuel de Jesus Soares</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report</atitle><jtitle>Journal of clinical neuroscience</jtitle><addtitle>J Clin Neurosci</addtitle><date>2020-09-01</date><risdate>2020</risdate><volume>79</volume><spage>169</spage><epage>171</epage><pages>169-171</pages><issn>0967-5868</issn><eissn>1532-2653</eissn><abstract>COVID-19 is the disease caused by Novel Coronavirus (SARS-CoV-2) infection and world current main public health problem, due to its easy transmissibility and multiple clinical presentations. The main symptoms reported worldwide are dry cough, dyspnea, and fever, as well as anosmia and ageusia. COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. Severe cases may evolve to thromboembolic and atheroembolic events, leading to stroke, myocardial infarction, pulmonary thromboembolism. Male, 28 years old, went for neurological appointment after presenting episode of intense headache, dysarthria, deviation of lip rhyme on appointment’s eve. Previously healthy, no comorbidities or risk factors. Underwent brain MRI and serum serological analysis. SARS-CoV-2 capacity of affecting brain homeostasis by breaking blood–brain barrier, makes it easier to develop ischemic or inflammatory damage, and invading central nervous system. Neurological symptoms and syndromes are the main consequences of COVID-19 pandemic and must be prevented through adequate clinical management.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>33070890</pmid><doi>10.1016/j.jocn.2020.07.034</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Betacoronavirus Case Report Coronavirus Infections - complications COVID-19 Humans Magnetic Resonance Imaging Male Multimodal Imaging Pandemics Pneumonia, Viral - complications SARS-CoV-2 Stroke Stroke - diagnostic imaging Stroke - etiology Tomography, X-Ray Computed Vasculitis Vasculitis - diagnostic imaging Vasculitis - etiology |
title | Vasculitis-related stroke in young as a presenting feature of novel coronavirus disease (COVID19) – Case report |
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