Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework

To conduct a systematic review and develop a conceptual framework on the mechanisms linking loneliness, social isolation, health outcomes and mortality. Electronic databases were systematically searched (PubMed, MEDLINE, Scopus and EMBASE) from inception to October 2018 followed by manual searching...

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Veröffentlicht in:Journal of the Royal Society of Medicine 2020-05, Vol.113 (5), p.185-192
Hauptverfasser: Hodgson, Sam, Watts, Isabella, Fraser, Simon, Roderick, Paul, Dambha-Miller, Hajira
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container_end_page 192
container_issue 5
container_start_page 185
container_title Journal of the Royal Society of Medicine
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creator Hodgson, Sam
Watts, Isabella
Fraser, Simon
Roderick, Paul
Dambha-Miller, Hajira
description To conduct a systematic review and develop a conceptual framework on the mechanisms linking loneliness, social isolation, health outcomes and mortality. Electronic databases were systematically searched (PubMed, MEDLINE, Scopus and EMBASE) from inception to October 2018 followed by manual searching to identify research on loneliness, social isolation and mortality in adults published in the English language. Articles were assessed for quality and synthesised into a conceptual framework using meta-ethnographical approaches. A total of 122 articles were included. These collated observational designs examining mediators and moderations of the association in addition to qualitative studies exploring potential mechanisms were included. A framework incorporating 18 discrete factors implicated in the association between loneliness, social isolation and mortality was developed. Factors were categorised into societal or individual, and sub-categorised into biological, behavioural and psychological. These findings emphasise the complex multidirectional relationship between loneliness, social isolation and mortality. Our conceptual framework may allow development of more holistic interventions, targeting many of the interdependent factors that contribute to poor outcomes for lonely and socially isolated people.
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subjects Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - mortality
Cardiovascular Diseases - psychology
Cause of Death
Databases, Factual
Delivery of Health Care
Female
Health Policy
Humans
Loneliness - psychology
Male
Policy Making
Psychology
Qualitative Research
Review
Risk Assessment
Social Isolation - psychology
Survival Analysis
United Kingdom
title Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework
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