Basic Mechanisms of JAK Inhibition

Most recently, with advances in our understanding of cell signalling pathways, we can target small molecules associated with intracellular signal transduction.1 These orally available drugs form a new category of treatment known as targeted synthetic DMARDs (tsDMARDs).2 The first drug class within t...

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Veröffentlicht in:	Mediterranean journal of rheumatology 2020-06, Vol.31 (Suppl 1), p.100-104
Hauptverfasser:	Lin, Chung Ma, Cooles, Faye Ah, Isaacs, John D
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical trials Cytokines Disease Drugs Enzymes Gene expression Growth factors Kinases Mutation Review Rheumatoid arthritis Signal transduction
Online-Zugang:	Volltext
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