Transcription factor 21 expression in injured podocytes of glomerular diseases

Transcription factor 21 (TCF21) is one of the essential transcription factors in kidney development. To elucidate its influence on glomerular disease, we have investigated TCF21 expression in human and rat kidney tissue, and its urinary concentration. Immunohistological analysis suggested the highes...

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Veröffentlicht in:	Scientific reports 2020-07, Vol.10 (1), p.11516-11516, Article 11516
Hauptverfasser:	Usui, Joichi, Yaguchi, Misa, Yamazaki, Satoshi, Takahashi-Kobayashi, Mayumi, Kawamura, Tetsuya, Kaneko, Shuzo, Seshan, Surya V., Ronco, Pierre, Yamagata, Kunihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4022 692/4022/1585 Actin Actin Cytoskeleton - genetics Adult Animal models Animal tissues Animals Apoptosis Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - urine Cytoskeleton Disease Models, Animal Female Humanities and Social Sciences Humans Kidney Diseases - genetics Kidney Diseases - pathology Kidney Diseases - urine Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Kidneys Life Sciences Male Mice Middle Aged multidisciplinary Nephrotic syndrome Nephrotic Syndrome - genetics Nephrotic Syndrome - urine Podocytes - metabolism Podocytes - pathology Proteinuria - genetics Rats Science Science (multidisciplinary) Severity of Illness Index Transcription factors Urinary Tract - metabolism Urinary Tract - pathology
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