Extraordinary Creatinine Level: A Case Report
Creatinine, an amino acid derived from creatine, has been traditionally used to assess kidney function. However, its levels are significantly affected by nutritional status, muscle mass, age, and sex of an individual. The effect of creatinine levels on human physiology is not completely understood,...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2020-07, Vol.12 (7) |
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| creator | Asif, Abuzar A Hussain, Habiba Chatterjee, Tulika |
| description | Creatinine, an amino acid derived from creatine, has been traditionally used to assess kidney function. However, its levels are significantly affected by nutritional status, muscle mass, age, and sex of an individual. The effect of creatinine levels on human physiology is not completely understood, and no correlation has been established between high creatinine levels and physiological equilibrium. We describe a case of a 27-year-old Hispanic male who presented with extremely elevated serum creatinine level (>37 mg/dL) with minimal symptoms of uremia and relatively fair functional status, eventually requiring hemodialysis. To our knowledge, based on a thorough review of the literature using PubMed, Medline, and Google Scholar, only four other cases have been reported with a creatinine level higher than that of our patient. A brief discussion on the utility of serum creatinine levels to assess mortality is provided using examples from similar case reports. |
| doi_str_mv | 10.7759/cureus.9076 |
| format | Article |
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However, its levels are significantly affected by nutritional status, muscle mass, age, and sex of an individual. The effect of creatinine levels on human physiology is not completely understood, and no correlation has been established between high creatinine levels and physiological equilibrium. We describe a case of a 27-year-old Hispanic male who presented with extremely elevated serum creatinine level (>37 mg/dL) with minimal symptoms of uremia and relatively fair functional status, eventually requiring hemodialysis. To our knowledge, based on a thorough review of the literature using PubMed, Medline, and Google Scholar, only four other cases have been reported with a creatinine level higher than that of our patient. 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This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2020, Asif et al. 2020 Asif et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c283t-887be69958f1bc023112dce4ca3a48f440e68fa10291d94c470edeca7486c7073</citedby><cites>FETCH-LOGICAL-c283t-887be69958f1bc023112dce4ca3a48f440e68fa10291d94c470edeca7486c7073</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357312/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357312/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Asif, Abuzar A</creatorcontrib><creatorcontrib>Hussain, Habiba</creatorcontrib><creatorcontrib>Chatterjee, Tulika</creatorcontrib><title>Extraordinary Creatinine Level: A Case Report</title><title>Curēus (Palo Alto, CA)</title><description>Creatinine, an amino acid derived from creatine, has been traditionally used to assess kidney function. However, its levels are significantly affected by nutritional status, muscle mass, age, and sex of an individual. The effect of creatinine levels on human physiology is not completely understood, and no correlation has been established between high creatinine levels and physiological equilibrium. We describe a case of a 27-year-old Hispanic male who presented with extremely elevated serum creatinine level (>37 mg/dL) with minimal symptoms of uremia and relatively fair functional status, eventually requiring hemodialysis. To our knowledge, based on a thorough review of the literature using PubMed, Medline, and Google Scholar, only four other cases have been reported with a creatinine level higher than that of our patient. A brief discussion on the utility of serum creatinine levels to assess mortality is provided using examples from similar case reports.</description><subject>Acidosis</subject><subject>Anemia</subject><subject>Antibodies</subject><subject>Asymptomatic</subject><subject>Blood platelets</subject><subject>Blood pressure</subject><subject>Cardiac stress tests</subject><subject>Case reports</subject><subject>Chronic illnesses</subject><subject>Creatinine</subject><subject>Electrocardiography</subject><subject>Electrolytes</subject><subject>Healthcare Technology</subject><subject>Hemodialysis</subject><subject>Hemoglobin</subject><subject>Hypertension</subject><subject>Internal Medicine</subject><subject>Kidney diseases</subject><subject>Laboratories</subject><subject>Metabolism</subject><subject>Mortality</subject><subject>Nephrology</subject><subject>Nutritional status</subject><subject>Peritoneal dialysis</subject><subject>Potassium</subject><subject>Ultrasonic imaging</subject><subject>Uremia</subject><subject>Urine</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkFtLw0AQhRdRbKl98g8EfJTUvSW764NQQr1AQBB9Xjabiaa02bqbFP33bkkRfZoZ5syZj4PQJcELITJ1YwcPQ1goLPITNKUkl6kkkp_-6SdoHsIaY0ywoFjgczRhNBdxyKYoXX313jhft53x30nhwfRt13aQlLCHzW2yTAoTIHmBnfP9BTprzCbA_Fhn6O1-9Vo8puXzw1OxLFNLJetTKUUFuVKZbEhlMWWE0NoCt4YZLhvOMeSyMQRTRWrFLRcYarBGcJnbCMZm6G703Q3VFuJpFyE3eufbbaTUzrT6_6ZrP_S722vBMsEIjQZXRwPvPgcIvV67wXeRWVNOFROKSRVV16PKeheCh-b3A8H6EK8e49WHeNkPPh5sPw</recordid><startdate>20200708</startdate><enddate>20200708</enddate><creator>Asif, Abuzar A</creator><creator>Hussain, Habiba</creator><creator>Chatterjee, Tulika</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20200708</creationdate><title>Extraordinary Creatinine Level: A Case Report</title><author>Asif, Abuzar A ; Hussain, Habiba ; Chatterjee, Tulika</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c283t-887be69958f1bc023112dce4ca3a48f440e68fa10291d94c470edeca7486c7073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acidosis</topic><topic>Anemia</topic><topic>Antibodies</topic><topic>Asymptomatic</topic><topic>Blood platelets</topic><topic>Blood pressure</topic><topic>Cardiac stress tests</topic><topic>Case reports</topic><topic>Chronic illnesses</topic><topic>Creatinine</topic><topic>Electrocardiography</topic><topic>Electrolytes</topic><topic>Healthcare Technology</topic><topic>Hemodialysis</topic><topic>Hemoglobin</topic><topic>Hypertension</topic><topic>Internal Medicine</topic><topic>Kidney diseases</topic><topic>Laboratories</topic><topic>Metabolism</topic><topic>Mortality</topic><topic>Nephrology</topic><topic>Nutritional status</topic><topic>Peritoneal dialysis</topic><topic>Potassium</topic><topic>Ultrasonic imaging</topic><topic>Uremia</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asif, Abuzar A</creatorcontrib><creatorcontrib>Hussain, Habiba</creatorcontrib><creatorcontrib>Chatterjee, Tulika</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asif, Abuzar A</au><au>Hussain, Habiba</au><au>Chatterjee, Tulika</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extraordinary Creatinine Level: A Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2020-07-08</date><risdate>2020</risdate><volume>12</volume><issue>7</issue><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Creatinine, an amino acid derived from creatine, has been traditionally used to assess kidney function. However, its levels are significantly affected by nutritional status, muscle mass, age, and sex of an individual. The effect of creatinine levels on human physiology is not completely understood, and no correlation has been established between high creatinine levels and physiological equilibrium. We describe a case of a 27-year-old Hispanic male who presented with extremely elevated serum creatinine level (>37 mg/dL) with minimal symptoms of uremia and relatively fair functional status, eventually requiring hemodialysis. To our knowledge, based on a thorough review of the literature using PubMed, Medline, and Google Scholar, only four other cases have been reported with a creatinine level higher than that of our patient. A brief discussion on the utility of serum creatinine levels to assess mortality is provided using examples from similar case reports.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><pmid>32670725</pmid><doi>10.7759/cureus.9076</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Acidosis Anemia Antibodies Asymptomatic Blood platelets Blood pressure Cardiac stress tests Case reports Chronic illnesses Creatinine Electrocardiography Electrolytes Healthcare Technology Hemodialysis Hemoglobin Hypertension Internal Medicine Kidney diseases Laboratories Metabolism Mortality Nephrology Nutritional status Peritoneal dialysis Potassium Ultrasonic imaging Uremia Urine |
| title | Extraordinary Creatinine Level: A Case Report |
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