Monitoring global changes in chromatin compaction states upon localized DNA damage, with tools of fluorescence anisotropy

In the eukaryotic nucleus, DNA, packaged in the form of chromatin, is subject to continuous damage. Chromatin has to be remodeled in order to repair such damage efficiently. But compact chromatin may also be more refractory to damage. Chromatin responses during DNA double strand break (DSB) repair h...

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Veröffentlicht in:Molecular biology of the cell 2020-06, Vol.31 (13), p.mbcE19080417-1410
Hauptverfasser: Kesavan, P S, Bohra, Darshika, Roy, Sitara, Mazumder, Aprotim
Format: Artikel
Sprache:eng
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