COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma

The oxidative phosphorylation machinery in mitochondria, which generates the main bioenergy pool in cells, includes four enzyme complexes for electron transport and ATP synthase. Among them, the cytochrome c oxidase (COX), which constitutes the fourth complex, has been suggested as the major regulat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancers 2020-06, Vol.12 (6), p.1646
Hauptverfasser:	Chu, Yu-De, Lin, Wey-Ran, Lin, Yang-Hsiang, Kuo, Wen-Hsin, Tseng, Chin-Ju, Lim, Siew-Na, Huang, Yen-Lin, Huang, Shih-Chiang, Wu, Ting-Jung, Lin, Kwang-Huei, Yeh, Chau-Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP synthase Bioenergetics Cancer therapies Cell activation Cell adhesion & migration Cell growth Cell migration Cell proliferation Cytochrome Cytochrome-c oxidase DNA microarrays Electron transport Extracellular signal-regulated kinase Hepatitis Hepatoma Kinases Liver cancer Medical prognosis Mitochondria Mitochondrial DNA Oxidative phosphorylation Phosphorylation Proteins Senescence Stathmin Tumorigenesis Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!