Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines

Hypochlorous acid (HOCl)-treated whole tumor cell lysates (Ox-L) have been shown to be more immunogenic when used as an antigen source for therapeutic dendritic cell (DC)-based vaccines, improving downstream immune responses both in vitro and in vivo. However, the mechanisms behind the improved immu...

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Veröffentlicht in:	Vaccines (Basel) 2020-06, Vol.8 (2), p.271, Article 271
Hauptverfasser:	Graciotti, Michele, Marino, Fabio, Pak, HuiSong, Baumgaertner, Petra, Thierry, Anne-Christine, Chiffelle, Johanna, Perez, Marta A. S., Zoete, Vincent, Harari, Alexandre, Bassani-Sternberg, Michal, Kandalaft, Lana E.
Format:	Artikel
Sprache:	eng
Schlagworte:	cancer vaccines dendritic cells Immunology immunopeptidomics immunotherapy Life Sciences & Biomedicine Medicine, Research & Experimental proteomics Research & Experimental Medicine Science & Technology
Online-Zugang:	Volltext
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