Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement

Orthodontic force-induced osteogenic differentiation and bone formation at tension side play a pivotal role in orthodontic tooth movement (OTM). Platelet-derived growth factor-BB (PDGF-BB) is a clinically proven growth factor during bone regeneration process with unclear mechanisms. Fibroblasts in p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2020-07, Vol.10 (1), p.11269-11269, Article 11269
Hauptverfasser:	Jin, Yuqin, Ding, Liang, Ding, Zhuang, Fu, Yong, Song, Yuxian, Jing, Yue, Li, Qiang, Zhang, Jianyun, Ni, Yanhong, Hu, Qingang
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/80 Alveolar bone Animals Becaplermin - metabolism Bioinformatics Bone growth Bone Regeneration Cell differentiation Computational Biology Fibroblasts Fibroblasts - metabolism Flow cytometry Growth factors Humanities and Social Sciences Imatinib Immunofluorescence Immunohistochemistry Janus kinase 2 Janus Kinase 2 - metabolism Ligaments Male multidisciplinary Orthodontics Osteogenesis Periodontal ligament Periodontal Ligament - cytology Periodontium Phenotypes Platelet-derived growth factor Platelet-derived growth factor BB Rats Rats, Sprague-Dawley Receptor, Platelet-Derived Growth Factor beta - metabolism Regeneration Science Science (multidisciplinary) Signal Transduction Stat3 protein STAT3 Transcription Factor - metabolism Teeth Tensile Strength Tension Tomography, X-Ray Computed Tooth Movement Techniques X-Ray Microtomography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!