Mechanisms underlying auditory processing deficits in Fragile X syndrome

Autism spectrum disorders (ASD) are strongly associated with auditory hypersensitivity or hyperacusis (difficulty tolerating sounds). Fragile X syndrome (FXS), the most common monogenetic cause of ASD, has emerged as a powerful gateway for exploring underlying mechanisms of hyperacusis and auditory...

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Veröffentlicht in:	The FASEB journal 2020-03, Vol.34 (3), p.3501-3518
Hauptverfasser:	McCullagh, Elizabeth A., Rotschafer, Sarah E., Auerbach, Benjamin D., Klug, Achim, Kaczmarek, Leonard K., Cramer, Karina S., Kulesza, Randy J., Razak, Khaleel A., Lovelace, Jonathan W., Lu, Yong, Koch, Ursula, Wang, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Auditory Perception - physiology auditory system Autism Spectrum Disorder - metabolism Autism Spectrum Disorder - physiopathology autism spectrum disorders circuit development Fragile X syndrome Fragile X Syndrome - metabolism Fragile X Syndrome - physiopathology Humans hyperacusis Models, Biological synaptic transmission
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