Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene

Abstract Neuroblastoma (NB) and malignant cutaneous melanoma (CMM) are neural crest cells (NCC)-derived tumors and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association studies (GWAS). We took a three-staged approach to conduct cross-disease me...

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Veröffentlicht in:	Carcinogenesis (New York) 2020-05, Vol.41 (3), p.284-295
Hauptverfasser:	Avitabile, Marianna, Succoio, Mariangela, Testori, Alessandro, Cardinale, Antonella, Vaksman, Zalman, Lasorsa, Vito Alessandro, Cantalupo, Sueva, Esposito, Matteo, Cimmino, Flora, Montella, Annalaura, Formicola, Daniela, Koster, Jan, Andreotti, Virginia, Ghiorzo, Paola, Romano, Maria Fiammetta, Staibano, Stefania, Scalvenzi, Massimiliano, Ayala, Fabrizio, Hakonarson, Hakon, Corrias, Maria Valeria, Devoto, Marcella, Law, Matthew H, Iles, Mark M, Brown, Kevin, Diskin, Sharon, Zambrano, Nicola, Iolascon, Achille, Capasso, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms - genetics Adrenal Gland Neoplasms - pathology Cancer Biomarkers and Molecular Epidemiology Cell Differentiation - genetics Cell Movement - genetics Chromosomes, Human, Pair 1 - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study Humans Male Melanoma - genetics Melanoma - pathology Melanoma, Cutaneous Malignant Monocarboxylic Acid Transporters - genetics Neural Crest - pathology Neuroblastoma - genetics Neuroblastoma - pathology Polymorphism, Single Nucleotide - genetics Skin Neoplasms - genetics Skin Neoplasms - pathology Symporters - genetics
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